Evidence map›Paper›PMID 37663229›Full record

ArticleOpen medicine (Warsaw, Poland)2023

The function of Foxp1 represses β-adrenergic receptor transcription in the occurrence and development of bladder cancer through STAT3 activity.

Zhenshan Ding, Binbin Jiao, Xuelong Chen, Xing Chen, Yangtian Jiao, Jianfeng Wang, Xiaofeng Zhou

Abstract read
In one paragraph

Article in Open medicine (Warsaw, Poland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Zhenshan DingDepartment of Urology, China-Japan Friendship Hospital, No. 2, Yinghua East Road, Chaoyang District, Beijing 100029, China.
Binbin JiaoDepartment of Urology, China-Japan Friendship Hospital, Beijing 100029, China.
Xuelong ChenDepartment of Clinical Medicine, Peking University China-Japan Friendship School, Beijing 100029, China.
Xing ChenDepartment of Urology, China-Japan Friendship Hospital, Beijing 100029, China.
Yangtian JiaoDepartment of Urology, China-Japan Friendship Hospital, Beijing 100029, China.
Jianfeng WangDepartment of Urology, China-Japan Friendship Hospital, Beijing 100029, China.
Xiaofeng ZhouDepartment of Urology, China-Japan Friendship Hospital, Beijing 100029, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Bladder cancer is a common malignant tumor. FOXP1 has been found to be abnormally expressed in tumors such as renal cell carcinoma and endometrial cancer. Here, this investigated the biological roles of Foxp1 in the occurrence and development of bladder cancer. Patients with bladder cancer were obtained from China-Japan Friendship Hospital. Bladder cancer cell lines (5637, UMUC3, J82, and T24 cell) were used in this experiment. Foxp1 mRNA and protein expression levels in patients with bladder cancer were increased, compared with paracancerous tissue (normal). OS and DFS of Foxp1 low expression in patients with bladder cancer were higher than those of Foxp1 high expression. Foxp1 promoted bladder cancer cell growth

Indexed as

bladder cancerFoxp1STAT3Warburg effectβ-AR

Identifiers

PMID37663229
PMCPMC10473461

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.