Evidence map›Paper›PMID 37663111›Full record

ArticleTherapeutic advances in infectious disease

Hospitalization risk among patients with Mpox infection-a propensity score matched analysis.

Andrés F Henao-Martínez, Chloe M Orkin, Boghuma K Titanji, Alfonso J Rodriguez-Morales, Jorge L Salinas, Carlos Franco-Paredes, Jose Tuells, Daniel B Chastain

Open access · goldAbstract read
In one paragraph

Article in Therapeutic advances in infectious disease. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 3 pooled it
2.7field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 3 syntheses or guidelines pooled it, 19 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 8 institutions in 7 countries.

Andrés F Henao-MartínezUniversity of Colorado Anschutz Medical Campus, 12700 E. 19th Avenue, Mail Stop B168, Aurora, CO 80045, USA.ORCID https://orcid.org/0000-0001-7363-8652
Chloe M OrkinSHARE Collaborative, Queen Mary University of London, London, UK.
Boghuma K TitanjiDivision of Infectious Diseases, Emory University School of Medicine, Atlanta, GA, USA.
Alfonso J Rodriguez-MoralesMaster of Clinical Epidemiology and Biostatistics, Universidad Científica del Sur, Lima, Peru.ORCID https://orcid.org/0000-0001-9773-2192
Jorge L SalinasDivision of Infectious Diseases and Geographic Medicine, Stanford University, Stanford, CA, USA.
Carlos Franco-ParedesHospital Infantil de México, Ciudad de México, Mexico.
Jose TuellsDepartment of Community Nursing, Preventive Medicine and Public Health and History of Science, Universidad de Alicante, Alicante, Spain.
Daniel B ChastainDepartment of Clinical and Administrative Pharmacy, University of Georgia College of Pharmacy, Albany, GA, USA.ORCID https://orcid.org/0000-0002-4018-0195
Emory University · USGeorgia College & State University · USInstituto Conmemorativo Gorgas de Estudios de la Salud · PAQueen Mary University of London · GBStanford University · USUniversidad Científica del Sur · PEUniversity of Alicante · ESUniversity of Colorado Anschutz Medical Campus · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Monkeypox (Mpox) is a reemerging, neglected viral disease. By May 2023, worldwide Mpox cases surpassed 87,000. Predictive factors for hospitalization with Mpox are lacking. Objective: We aim to compare clinical characteristics and outcomes in hospitalized and nonhospitalized patients with Mpox infection. Design: A multicenter retrospective case-control cohort of patients with Mpox infection. Methods: We performed a propensity score match analysis from a global health network (TrinetX). We compare clinical characteristics and outcomes between hospitalized and nonhospitalized patients with Mpox. Results: Of 1477 patients, 6% were hospitalized, 52% required an ED visit, and 29% received treatment at urgent care. After propensity score matching, 80 patients remained in each group. Hospitalizations were more common among Black persons (51% Conclusion: Independent predictive factors of hospitalization in our cohort for Mpox included people who are Black with a diagnosis of HIV, severe proctitis, pain requiring opioids, and elevated lactate dehydrogenase. Greater recognition of factors associated with increased risk of Mpox severity and hospitalization is paramount.

Indexed as

HIV/AIDShospitalizationMonkeypox virusMpox

Identifiers

PMID37663111
PMCPMC10469242
OpenAlexW4386289265

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.