Evidence map›Paper›PMID 37662819›Full record

ArticleHeliyon2023

Natural polymers as potential P-glycoprotein inhibitors: Pre-ADMET profile and computational analysis as a proof of concept to fight multidrug resistance in cancer.

Kumaraswamy Gandla, Fahadul Islam, Mehrukh Zehravi, Anandakumar Karunakaran, Indu Sharma, M Akiful Haque, Sanjay Kumar, Kumar Pratyush, Sachin A Dhawale, Firzan Nainu and 6 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Heliyon, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
4.1field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 18 citations in OpenAlex.

  1. Potential ofFood science & nutrition · 2026
    Article
  2. Mechanistic insights into natural product-driven modulation of NLRP3-inflammasome signalling in metabolic syndrome.Inflammation research : official journal of the European Histamine Research Society ... [et al.] · 2026
    Review
  3. Article
  4. Review
  5. Review
  6. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 12 institutions in 6 countries.

Kumaraswamy GandlaDepartment of Pharmaceutical Analysis, Chaitanya (Deemed to be University), Himayath Nagar, Hyderabad 500075, Telangana, India.
Fahadul IslamDepartment of Pharmacy, Faculty of Allied Health Sciences, Daffodil International University, Dhaka 1207, Bangladesh.
Mehrukh ZehraviDepartment of Clinical Pharmacy Girls Section, Prince Sattam Bin Abdul Aziz University, Al-Kharj 11942, Saudi Arabia.
Anandakumar KarunakaranDepartment of Pharmaceutical Analysis, Vivekanandha Pharmacy College for Women, Beerachipalayam, Sankari West, Sankari, Salem, Tamil Nadu, - 637 303, India.
Indu SharmaDepartment of Physics, Career Point University, Hamirpur, Himachal Pradesh 176041, India.
M Akiful HaqueDepartment of Pharmaceutical Analysis, School of Pharmacy, Anurag University, Hyderabad, India.
Sanjay KumarDepartment of Pharmacognosy, Laureate Institute of Pharmacy, VPO Kathog, Dehra, Kangra, Himachal Pradesh 176031, India.
Kumar PratyushDepartment of Pharmaceutical Chemistry, Shri Vile Parle Kelavani Mandal's Institute of Pharmacy, Dhule, Maharashtra, 424001, India.
Sachin A DhawaleShreeyash Institute of Pharmaceutical Education and Research Aurangabad, 431 005, Maharashtra, India.
Firzan NainuDepartment of Pharmacy, Faculty of Pharmacy, Hasanuddin University, Makassar 90245, Indonesia.
Sharuk L KhanDepartment of Pharmaceutical Chemistry, N.B.S. Institute of Pharmacy, Ausa 413520, Maharashtra, India.
Md Rezaul IslamDepartment of Pharmacy, Faculty of Allied Health Sciences, Daffodil International University, Dhaka 1207, Bangladesh.
Kholoud Saad Al-MugrenDepartment of Physics, College of Science, Princess Nourah Bint Abdulrahman University, P.O. Box 84428 Riyadh 11671, Saudi Arabia.
Falak A SiddiquiDepartment of Pharmaceutical Chemistry, N.B.S. Institute of Pharmacy, Ausa 413520, Maharashtra, India.
Talha Bin EmranDepartment of Pathology and Laboratory Medicine, Warren Alpert Medical School & Legorreta Cancer Center, Brown University, Providence, RI 02912, USA.
Mayeen Uddin KhandakerCentre for Applied Physics and Radiation Technologies, School of Engineering and Technology, Sunway University, Bandar Sunway 47500, Selangor, Malaysia.
Advanced Numerical Research and Analysis Group · INDaffodil International University · BDBiological E (India) · INBrown University · USCareer Point University · INGovernment Medical College · INHasanuddin University · IDPrince Sattam Bin Abdulaziz University · SAPrincess Nourah bint Abdulrahman University · SAShri Vile Parle Kelavani Mandal · INSunway University · MYSwami Vivekanand College of Pharmacy · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

P-glycoprotein (P-gp) is known as the "

Indexed as

In silico-ADMETMDRMolecular dockingMolecular dynamic simulationNatural polymersP-glycoproteinToxicity

Identifiers

PMID37662819
PMCPMC10472248
OpenAlexW4386122819

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.