Evidence map›Paper›PMID 37662597›Full record

ArticleFrontiers in nutrition2023

Comparing effects of beetroot juice and Mediterranean diet on liver enzymes and sonographic appearance in patients with non-alcoholic fatty liver disease: a randomized control trials.

Hawal Lateef Fateh, Sameeah Abdulrahman Rashid, Sarmad S Muhammad, Sabah H Al-Jaf, Ayad M Ali

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in Frontiers in nutrition, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06627114 (Effectiveness of Nutrition Education Program and Omega-3 Supplementation on Body Weight, Liver Enzymes, Lipid Profile Among Non-Alcoholic Fatty Liver Disease Patients), which is not on this map. Cited by 4 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 4 pooled it
2.1field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06627114 nacompletednot on this mapstarted 2024, after this paper: background citation

Effectiveness of Nutrition Education Program and Omega-3 Supplementation on Body Weight, Liver Enzymes, Lipid Profile Among Non-Alcoholic Fatty Liver Disease Patients

TypeinterventionalSponsorHawler Medical UniversityRan2024 to 2025Enrolled159ConditionsNon-alcoholic Fatty Liver Disease (NAFLD), Omega-3 Supplementation, Nutrition Education ProgramArmsnutrition education program, Omega 3 fatty acids, control group
3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 4 syntheses or guidelines pooled it, 10 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Hawal Lateef FatehNursing Department, Kalar Technical College, Sulaimani Polytechnic University, Sulaymaniyah, Iraq.
Sameeah Abdulrahman RashidDepartment of Surgery, College of Medicine, Hawler Medical University, Erbil, Iraq.
Sarmad S MuhammadMedical Laboratory Technology Department, Kalar Technical College, Sulaimani Polytechnic University, Sulaymaniyah, Iraq.
Sabah H Al-JafDepartment of Chemistry, College of Science, University of Garmian, Sulaimani, Iraq.
Ayad M AliDepartment of Chemistry, College of Science, University of Garmian, Sulaimani, Iraq.
Kurdistan Regional Government · IQSulaimani Polytechnic University · IQHawler Medical University · IQ

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: In both developed and developing countries, non-alcoholic fatty liver disease (NAFLD) has lately risen to the top of the list of chronic liver illnesses. Although there is no permanent cure, early management, diagnosis, and treatment might lessen its effects. The purpose of conducting the current study is to compare the effects of beetroot juice and the Mediterranean diet on the lipid profile, level of liver enzymes, and liver sonography in patients with NAFLD. Methods: In this randomized controlled trial, 180 people with a mean age of (45.19 ± 14.94) years participated. Participants ranged in age from 19 to 73. The mean weight before intervention was (82.46 ± 5.97) kg, while the mean weight after intervention was roughly (77.88 ± 6.26) kg. The trial lasted for 12 weeks. The participants were split into four groups: control, a Mediterranean diet with beet juice (BJ + MeD), Mediterranean diet alone (MeD), and beetroot juice (BJ). The Mediterranean diet included fruits, vegetables, fish, poultry, and other lean meats (without skin), sources of omega-3 fatty acids, nuts, and legumes. Beetroot juice had 250 mg of beetroot. Data analysis was done using SPSS software (version 26.0). Results: Following the intervention, Serum Bilirubin, alkaline phosphatase (ALP), alanine transaminase (ALT), serum cholesterol (CHOL), triglyceride (TG), and low-density lipoprotein (LDL) levels were significantly decreased in the BJ + MeD, BJ, and MeD groups ( Conclusion: The research findings indicate a significant reduction in hepatic steatosis among the groups receiving beetroot juice (BJ) and beetroot juice combined with the Mediterranean diet (BJ + MeD). This suggests that beetroot juice holds potential as an effective treatment for non-alcoholic fatty liver disease (NAFLD) in adults. Furthermore, the combination of beetroot juice with the Mediterranean diet showed enhanced efficacy in addressing NAFLD.

Indexed as

beetroot juicemediterranean dietNAFLDnonalcoholic fatty liverRCT

Identifiers

PMID37662597
PMCPMC10469647
OpenAlexW4385930862

What OpenQuestion holds

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LicenceCC BY
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.