Evidence map›Paper›PMID 37662595›Full record

ArticleFrontiers in nutrition2023

A comparative absorption study of sucrosomial

Aasiya Bano, Saida Abrar, Elisa Brilli, Germano Tarantino, Ali Akbar Bugti, Marco Fabbrini, Gabriele Conti, Silvia Turroni, Mahroo Bugti, Fauzia Afridi and 7 more

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in Frontiers in nutrition, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05706259 (A Comparative Vitamin D Bioavailability Study Following Supplementation of an Orodispersible, Chewable Tablet and Soft Gelatin Capsule Vitamin D3 Supplementation in Vitamin D Deficient Healthy Adults), which is not on this map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.5field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05706259 nacompletednot on this map

A Comparative Vitamin D Bioavailability Study Following Supplementation of an Orodispersible, Chewable Tablet and Soft Gelatin Capsule Vitamin D3 Supplementation in Vitamin D Deficient Healthy Adults

TypeinterventionalSponsorLiaquat University of Medical & Health SciencesRan2023 to 2023Enrolled40ConditionsVitamin D DeficiencyArmsSoft gelatin 200000 IU vitamin D3 capsule, Orodispersible (sachet) 200000 IU vitamin D3
3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 6 citations in OpenAlex.

  1. Trial
  2. Review
  3. Review
  4. Article
  5. Review
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 8 institutions in 3 countries.

Aasiya Bano *PEOC, Department of Health, Balochistan, Quetta, Pakistan.
Saida Abrar *Department of Obstetrics and Gynaecology, Lady Reading Hospital (LRH), Peshawar, Pakistan.
Elisa BrilliDepartment of R&D, PharmaNutra S.p.A, Pisa, Italy.
Germano TarantinoDepartment of R&D, PharmaNutra S.p.A, Pisa, Italy.
Ali Akbar BugtiDepartment of General Surgery, Bolan Medical Complex Hospital (BMCH), Quetta, Pakistan.
Marco FabbriniUnit of Microbiome Science and Biotechnology, Department of Pharmacy and Biotechnology, University of Bologna, Bologna, Italy.
Gabriele ContiUnit of Microbiome Science and Biotechnology, Department of Pharmacy and Biotechnology, University of Bologna, Bologna, Italy.
Silvia TurroniUnit of Microbiome Science and Biotechnology, Department of Pharmacy and Biotechnology, University of Bologna, Bologna, Italy.
Mahroo BugtiDepartment of Obstetrics and Gynaecology, BMCH, Quetta, Pakistan.
Fauzia AfridiDepartment of Obstetrics and Gynaecology, Khyber Teaching Hospital, Peshawar, Pakistan.
Shah MureedDepartment of Paediatrics, BMCH, Quetta, Pakistan.
Hakeem ZadaMubarak Diagnostic Laboratory and Research Center, Peshawar, Pakistan.
Ikram Din UjjanDepartment of Pathology, Liaquat University of Medical and Health Sciences (LUMHS), Jamshoro, Pakistan.
Saadia AshrafDepartment of Pulmonology, Khyber Teaching Hospital, Peshawar, Pakistan.
Aamir GhafoorDepartment of Gastroenterology, LRH, Peshawar, Pakistan.
Saeed KhanDepartment of Molecular Pathology, Dow University of Health Sciences, Karachi, Pakistan.
Amjad KhanNuffield Division of Clinical Laboratory Sciences, Radcliffe Department of Medicine, University of Oxford, Oxford, United Kingdom.
Bolan Medical College · PKUniversity of Bologna · ITKhyber Teaching Hospital · PKLady Reading Hospital · PKDow University of Health Sciences · PKLiaquat University of Medical & Health Sciences · PKUniversity of Balochistan · PKUniversity of Oxford · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Vitamin D (Vit D) deficiency (VDD), associated with diverse health conditions, is commonly treated with Vit D3 supplements. However, the gastrointestinal (GI) absorption of Vit D3 in different formulations has not been well studied. Objective: We aimed to compare the absorption of an innovative phospholipids-sucrester matrix biodelivery vehicle-based (sucrosomial Methods: In study 1, 25 subjects were randomized to receive a weekly single dose of 200,000 IU of sucrosomial Results: In study 1, after 2 weeks, circulatory 25(OH)D levels increased significantly in both Vit D3 treatment groups ( Conclusion: Our results suggest that the sucrosomial Clinical trial registration: clinicaltrials.gov, identifier: NCT05706259.

Indexed as

orodispersible vitamin D3sucrosomial® vitamin D3vitamin D3 absorptionvitamin D3 supplementationvitamin D deficiency

Identifiers

PMID37662595
PMCPMC10469777
OpenAlexW4385902938

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.