Evidence map›Paper›PMID 37662555›Full record

ArticleJournal of the Royal Statistical Society. Series C, Applied statistics2023

Estimating a brain network predictive of stress and genotype with supervised autoencoders.

Austin Talbot, David Dunson, Kafui Dzirasa, David Carlson

Open access · hybridAbstract read
In one paragraph

Article in Journal of the Royal Statistical Society. Series C, Applied statistics, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.9field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 6 citations in OpenAlex.

  1. A widespread internal brain state for fentanyl withdrawal.bioRxiv : the preprint server for biology · 2026
    Article
  2. Generative Principal Component Regression via Variational Inference.IEEE transactions on signal processing : a publication of the IEEE Signal Processing Society · 2026
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Austin TalbotPillar Biosciences Inc., Natick, MA, USA.ORCID https://orcid.org/0000-0001-6207-1304
David DunsonDepartment of Statistical Science, Duke University, Durham, NC, USA.
Kafui DzirasaDepartment of Psychiatry and Behavioral Sciences, Duke University, Durham, NC, USA.
David CarlsonDepartment of Civil and Environmental Engineering, Duke University, Durham, NC, USA.
Duke University · USHoward Hughes Medical Institute · US

Funding

Uncovering Population-Level Cellular Relationships to Behavior via Mesoscale NetworksR01EB026937 · NIBIB · DUKE UNIVERSITY · PI CARLSON, DAVID E · 2019 to 2019
$1.1M
CRCNS: Geometry-based Brain Connectome AnalysisR01MH118927 · NIMH · DUKE UNIVERSITY · PI DUNSON, DAVID BRIAN, ZHANG, ZHENGWU · 2018 to 2020
$945k
NIBIB NIH HHS R01 EB026937NIMH NIH HHS R01 MH118927
6 · The paper itself

Abstract

Targeted brain stimulation has the potential to treat mental illnesses. We develop an approach to help design protocols by identifying relevant multi-region electrical dynamics. Our approach models these dynamics as a superposition of latent networks, where the latent variables predict a relevant outcome. We use supervised autoencoders (SAEs) to improve predictive performance in this context, describe the conditions where SAEs improve predictions, and provide modelling constraints to ensure biological relevance. We experimentally validate our approach by finding a network associated with stress that aligns with a previous stimulation protocol and characterizing a genotype associated with bipolar disorder.

Indexed as

dimensionality reductionfactor analysisjoint modelneurosciencesupervised autoencoders

Identifiers

PMID37662555
PMCPMC10474874
OpenAlexW4377287648

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.