Evidence map›Paper›PMID 37662365›Full record

ArticlebioRxiv : the preprint server for biology2023

Local and dynamic regulation of neuronal glycolysis

Aaron D Wolfe, John N Koberstein, Chadwick B Smith, Melissa L Stewart, Marc Hammarlund, Anthony Hyman, Philip Js Stork, Richard Goodman, Daniel A Colón-Ramos

Open access · greenAbstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 2 countries.

Aaron D WolfeDepartment of Neuroscience and Department of Cell Biology, Yale University School of Medicine; New Haven, CT 06536, USA.
John N KobersteinVollum Institute, Oregon Health & Science University, Portland, OR 97239, USA.
Chadwick B SmithVollum Institute, Oregon Health & Science University, Portland, OR 97239, USA.
Melissa L StewartVollum Institute, Oregon Health & Science University, Portland, OR 97239, USA.
Marc HammarlundDepartment of Neuroscience and Department of Cell Biology, Yale University School of Medicine; New Haven, CT 06536, USA.
Anthony HymanMax Planck Institute of Molecular Cell Biology and Genetics, Pfotenhauerstraße 108, Dresden, Germany.
Philip Js StorkVollum Institute, Oregon Health & Science University, Portland, OR 97239, USA.
Richard GoodmanDepartment of Neuroscience and Department of Cell Biology, Yale University School of Medicine; New Haven, CT 06536, USA.
Daniel A Colón-RamosDepartment of Neuroscience and Department of Cell Biology, Yale University School of Medicine; New Haven, CT 06536, USA.
Oregon Health & Science University · USYale University · USMax Planck Institute of Molecular Cell Biology and Genetics · DE

Funding

Enhancing and expanding the CGC Strain CollectionP40OD010440 · OD · UNIVERSITY OF MINNESOTA · PI Aric L Daul, Ann E. Rougvie · 2012 to 2026
$7.5M
Powering the Brain: the Cell Biology of NeuroenergeticsDP1NS111778 · NINDS · YALE UNIVERSITY · PI COLON-RAMOS, DANIEL A · 2018 to 2022
$5.9M
Examination of the cell biology of the synapse and behaviorR35NS132156 · NINDS · YALE UNIVERSITY · PI DANIEL A COLON-RAMOS · 2023 to 2026
$4.6M
New Mechanisms in Axon RegenerationR01NS094219 · NINDS · YALE UNIVERSITY · PI HAMMARLUND, MARC · 2015 to 2025
$4.0M
Evaluation of Novel Axon Regeneration Targets for Spinal Cord injury TherapyR01NS098817 · NINDS · YALE UNIVERSITY · PI HAMMARLUND, MARC, STRITTMATTER, STEPHEN M · 2016 to 2020
$1.4M
NIH HHS P40 OD010440NINDS NIH HHS DP1 NS111778NINDS NIH HHS R01 NS094219NINDS NIH HHS R01 NS098817NINDS NIH HHS R35 NS132156
6 · The paper itself

Abstract

Energy metabolism supports neuronal function. While it is well established that changes in energy metabolism underpin brain plasticity and function, less is known about how individual neurons modulate their metabolic states to meet varying energy demands. This is because most approaches used to examine metabolism in living organisms lack the resolution to visualize energy metabolism within individual circuits, cells, or subcellular regions. Here we adapted a biosensor for glycolysis, HYlight, for use in

Identifiers

PMID37662365
PMCPMC10473759
OpenAlexW4386203593

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.