Evidence map›Paper›PMID 37662276›Full record

ArticlebioRxiv : the preprint server for biology2024

Brief and diverse excitotoxic insults cause an increase in neuronal nuclear membrane permeability in the neonatal brain.

P Suryavanshi, R Langton, K Fairhead, J Glykys

Open access · greenAbstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

P SuryavanshiDepartment of Pediatrics, University of Iowa, Iowa City, IA.ORCID 0000-0001-6904-7294
R LangtonDepartment of Pediatrics, University of Iowa, Iowa City, IA.ORCID 0000-0002-5543-3925
K FairheadBiomedical Sciences, College of Liberal Arts and Sciences, University of Iowa, Iowa City, IA.
J GlykysDepartment of Pediatrics, University of Iowa, Iowa City, IA.ORCID 0000-0002-1499-9172
University of Iowa · US

Funding

University of Iowa Hawkeye Intellectual and Developmental Disabilities Research Center (Hawk-IDDRC)P50HD103556 · NICHD · UNIVERSITY OF IOWA · PI Lane Strathearn · 2021 to 2026
$8.5M
Water and chloride movement in neurons during seizure activityR01NS115800 · NINDS · UNIVERSITY OF IOWA · PI GLYKYS, JOSEPH C. · 2020 to 2024
$2.1M
NICHD NIH HHS P50 HD103556NINDS NIH HHS R01 NS115800
6 · The paper itself

Abstract

Neuronal swelling after excitotoxic insults is implicated in neuronal injury and death in the developing brain, yet mitigating brain edema with osmotic and surgical interventions yields poor clinical outcomes. Importantly, neuronal swelling and its downstream consequences during early brain development remain poorly investigated. Using multiphoton Ca

Indexed as

Ca2+ dynamicsCytotoxic edemaNMDAR activationnuclear dysregulationOGDseizures

Identifiers

PMID37662276
PMCPMC10473591
OpenAlexW4386097961

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.