ArticleFrontiers in neurology2023
Case report: Reversible splenial lesion syndrome caused by diquat poisoning.
Article in Frontiers in neurology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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6 citing papers in PubMed, 14 citations in OpenAlex.
- Some novel causes and clinical characteristics of reversible splenial lesion syndrome- found in children.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2025Article
- Construction and validation of a nomogram model to predict mortality risk in patients with acute diquat poisoning.American journal of translational research · 2025Article
- Diquat poisoning, maybe another cause of osmotic demyelination syndrome: case report and literature review.Frontiers in medicine · 2025Article
- Febrile neutropenia induced by adjuvant radiotherapy for a patient with breast cancer accompanied with reversible splenial lesion syndrome (RESLES, TypeI): a case report.BMC neurology · 2024Article
- Bilateral hearing loss as the initial presentation of reversible Wernicke's encephalopathy with splenial lesion.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2024Article
- Neuroimaging features of psilocybin-induced toxic-metabolic encephalopathy in an adolescent.BMJ case reports · 2024Article
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11 authors at 4 institutions in 1 country.
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No grant is acknowledged in the PubMed record.
Abstract
Diquat (DQ), chemically known as 1,1 '-ethylene-2,2' -bipyridine, is a non-selective herbicide for leaf removal and drying. It has toxic effects on central nervous system cells, and toxic neurological lesions include axonal degeneration and pontine myelolysis. At the same time, DQ can also affect the activity of dopaminergic nerve cells through oxidative stress, causing degeneration and reducing dopamine uptake. With the increasing application of DQ in agricultural production, the clinical reports of neurotoxicity caused by acute DQ poisoning are also increasing. At present, DQ rapid-phase-related toxic encephalopathy mainly involves the pons, midbrain, basal ganglia, thalamus and other brain regions. However, this case is unusual in that the lesion mainly involved the splenium of the corpus callosum. It is also the first time to be reported.
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