Evidence map›Paper›PMID 37661862›Full record

ReviewEpigenomics2023

Clinically informative microRNAs for SARS-CoV-2 infection.

Sercan Ergün, Ramamoorthy Sankaranarayanan, Nina Petrović

Open access · greenAbstract readReview
In one paragraph

Review in Epigenomics, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
2.6field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 11 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 3 institutions in 3 countries.

Sercan ErgünDepartment of Medical Biology, Faculty of Medicine, Ondokuz Mayis University, Samsun, Turkey.ORCID 0000-0002-6733-9848
Ramamoorthy SankaranarayananDepartment of Plant Sciences, School of Biological Sciences, Madurai Kamaraj University, Tamil Nadu, India.ORCID 0000-0002-0661-2468
Nina PetrovićLaboratory for Radiobiology & Molecular Genetics, Department of Health & Environment, 'VINČA' Institute of Nuclear Sciences - National Institute of the Republic of Serbia, University of Belgrade, Mike Petrovića Alasa 12-14, Belgrade, 11001, Serbia.ORCID 0000-0003-2503-1228
Madurai Kamaraj University · INOndokuz Mayıs University · TRUniversity of Belgrade · RS

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

COVID-19 is a viral respiratory infection induced by the newly discovered coronavirus SARS-CoV-2. miRNA is an example of a strong and direct regulator of a gene's transcriptional activity. The interaction between miRNAs and their target molecules is responsible for homeostasis. Virus-derived and host-derived miRNAs are involved in the activity of hiding from immune system cells, inducing the inflammatory reaction through interplay with associated genes, during SARS-COV-2 infection. Interest in miRNAs has raised the comprehension of the machinery and pathophysiology of SARS-COV-2 infection. In this review, the effects and biological roles of miRNAs on SARS-CoV-2 pathogenicity and life cycle are described. The therapeutic potential of miRNAs against SARS-CoV-2 infection are also mentioned.

Indexed as

COVID-19MicroRNAsHumansInflammationSARS-CoV-2MicroRNAsCOVID-19diagnosismicroRNASARS-CoV-2transcriptional regulationviral infection

Identifiers

PMID37661862
PMCPMC10476648
OpenAlexW4386407806

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.