Evidence map›Paper›PMID 37661831›Full record

ArticleJournal of medical screening2024

The recalibration and redevelopment of a model to calculate patients' probability of completing a colonoscopy following an abnormal fecal test.

Amanda F Petrik, Eric S Johnson, Matthew Slaughter, Michael C Leo, Jamie Thompson, Rajasekhara R Mummadi, Ricardo Jimenez, Syed Akmal Hussain, Gloria Coronado

Abstract read
In one paragraph

Article in Journal of medical screening, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Trial
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Amanda F PetrikCenter for Health Research, Kaiser Permanente Northwest, Portland, Oregon, USA.ORCID 0000-0002-8891-6042
Eric S JohnsonCenter for Health Research, Kaiser Permanente Northwest, Portland, Oregon, USA.
Matthew SlaughterCenter for Health Research, Kaiser Permanente Northwest, Portland, Oregon, USA.
Michael C LeoCenter for Health Research, Kaiser Permanente Northwest, Portland, Oregon, USA.
Jamie ThompsonCenter for Health Research, Kaiser Permanente Northwest, Portland, Oregon, USA.
Rajasekhara R MummadiCenter for Health Research, Kaiser Permanente Northwest, Portland, Oregon, USA.
Ricardo JimenezSeaMar Community Health Centers, Seattle, Washington, USA.
Syed Akmal HussainSeaMar Community Health Centers, Seattle, Washington, USA.
Gloria CoronadoCenter for Health Research, Kaiser Permanente Northwest, Portland, Oregon, USA.

Funding

NW Center of Excellence & K12 in Patient Centered Learning Health Systems ScienceK12HS026370 · AHRQ · OREGON HEALTH & SCIENCE UNIVERSITY · PI EDEN, KAREN BEEKMAN, GUISE, JEANNE-MARIE · 2018 to 2022
$4.0M
Prediciting and addressing colonoscopy non-adherence in community settingsR01CA218923 · NCI · KAISER FOUNDATION RESEARCH INSTITUTE · PI CORONADO, GLORIA D · 2018 to 2022
$3.5M
AHRQ HHS K12 HS026370NCI NIH HHS R01 CA218923
6 · The paper itself

Abstract

objectivesFecal immunochemical testing (FIT) is an effective screening tool for colorectal cancer. If an FIT is abnormal, a follow-up colonoscopy is necessary to remove polyps or find cancers. We sought to develop a usable risk prediction model to identify patients unlikely to complete a colonoscopy following an abnormal FIT test.

methodsWe recalibrated and then redeveloped a prediction model in federally qualified health centers (FQHCs), using a retrospective cohort of patients aged 50-75 with an abnormal FIT test and clinical data. Logistic and Cox regressions were used to recalibrate and then redevelop the model.

resultsThe initial risk model used data from eight FQHCs (26 clinics) including 1723 patients. When we applied the model to a single large FQHC (34 clinics, 884 eligible patients), the model did not recalibrate successfully (c-statistic dropped more than 0.05, from 0.66 to 0.61). The model was redeveloped in the same FQHC in a cohort of 1401 patients with a c-statistic of 0.65.

conclusionsThe original model developed in a group of FQHCs did not adequately recalibrate in the single large FQHC. Health system, patient characteristics or data differences may have led to the inability to recalibrate the model. However, the redeveloped model provides an adequate model for the single FQHC.

Indexed as

Colorectal NeoplasmsColonoscopyEarly Detection of CancerHumansMass ScreeningOccult BloodRetrospective Studiescancer preventioncolonoscopycolorectal cancer screeningfecal testingRisk prediction

Identifiers

PMID37661831
PMCPMC10909915

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.