Evidence map›Paper›PMID 37661311›Full record

SynthesisInternational journal of stroke : official journal of the International Stroke Society2024

Recurrence of cervical artery dissection: A systematic review and meta-analysis.

Elizabeth Lounsbury, Naomi Niznick, Ranjeeta Mallick, Brian Dewar, Alexandra Davis, Dean A Fergusson, Dar Dowlatshahi, Michel Shamy

Open access · hybridAbstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in International journal of stroke : official journal of the International Stroke Society, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
2.7field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 13 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Elizabeth LounsburyDepartment of Medicine, University of Ottawa, Ottawa, ON, Canada.
Naomi NiznickDepartment of Medicine, University of Ottawa, Ottawa, ON, Canada.ORCID 0000-0003-0935-9135
Ranjeeta MallickOttawa Hospital Research Institute, Ottawa, ON, Canada.
Brian DewarOttawa Hospital Research Institute, Ottawa, ON, Canada.ORCID 0000-0002-9222-5420
Alexandra DavisLibrary Services, Royal Ottawa Mental Health Centre, Ottawa, ON, Canada.
Dean A FergussonDepartment of Medicine, University of Ottawa, Ottawa, ON, Canada.
Dar DowlatshahiDepartment of Medicine, University of Ottawa, Ottawa, ON, Canada.ORCID 0000-0003-1379-3612
Michel ShamyDepartment of Medicine, University of Ottawa, Ottawa, ON, Canada.ORCID 0000-0002-0085-6816
University of Ottawa · CAOttawa Hospital · CARoyal Ottawa Mental Health Centre · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

background and purposeCervical artery dissection (CAD) involving the carotid or vertebral arteries is an important cause of stroke in younger patients. The purpose of this systematic review is to assess the risk of recurrent CAD.

methodsA systematic review and meta-analysis was conducted on studies in which patients experienced radiographically confirmed dissections involving an extracranial segment of the carotid or vertebral artery and in whom CAD recurrence rates were reported.

resultsData were extracted from 29 eligible studies (n = 5898 patients). Analysis of outcomes was performed by pooling incidence rates with random effects models weighting by inverse of variance. The incidence of recurrent CAD was 4% overall (95% confidence interval (CI) = 3-7%), 2% at 1 month (95% CI = 1-5%), and 7% at 1 year in studies with sufficient follow-up (95% CI = 4-13%). The incidence of recurrence associated with ischemic events was 2% (95% CI = 1-3%).

conclusionsWe found low rates of recurrent CAD and even lower rates of recurrence associated with ischemia. Further patient-level data and clinical subgroup analyses would improve the ability to provide patient-level risk stratification.

Indexed as

RecurrenceVertebral Artery DissectionCarotid Artery, Internal, DissectionHumansDissectionischemic strokeoutcomerecurrence

Identifiers

PMID37661311
PMCPMC10964388
OpenAlexW4386406873

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.