Evidence map›Paper›PMID 37661234›Full record

ArticlePediatric nephrology (Berlin, Germany)2024

Using aquapheresis with continuous hematocrit monitoring to guide ultrafiltration.

Michelle C Starr, Michelle Voivodas, David S Hains

Open access · greenAbstract read
In one paragraph

Article in Pediatric nephrology (Berlin, Germany), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.2field-weighted citation impact, top 45% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Michelle C StarrDivision of Pediatric Nephrology, Department of Pediatrics, Indiana University School of Medicine, 410 W 10Th Street, Suite 2000A, Indianapolis, IN, 46202, USA. mcstarr@iu.edu.ORCID 0000-0001-9412-8950
Michelle VoivodasDivision of Pediatric Critical Care Medicine, Department of Pediatrics, Indiana University School of Medicine, Indianapolis, IN, USA.
David S HainsDivision of Pediatric Nephrology, Department of Pediatrics, Indiana University School of Medicine, 410 W 10Th Street, Suite 2000A, Indianapolis, IN, 46202, USA.
Indiana University School of Medicine

Funding

CTSA K12 Program at Indiana UniversityK12TR004415 · NCATS · INDIANA UNIVERSITY INDIANAPOLIS · PI SAMIR KUMAR GUPTA · 2023 to 2026
$3.4M
Improving the prediction of bronchopulmonary dysplasia by identifying kidney-based risk factorsK23HL168362 · NHLBI · INDIANA UNIVERSITY INDIANAPOLIS · PI Michelle C Starr · 2024 to 2026
$547k
NCATS NIH HHS K12 TR004415NHLBI NIH HHS K23 HL168362
6 · The paper itself

Abstract

backgroundManagement of edema and volume overload in patients with hypoalbuminemia, either due to nephrotic syndrome or other disease processes, can be extremely challenging.

methodsWe describe the management of five patients with hypoalbuminemia and severe fluid overload using the Aquadex FlexFlow device with continuous hematocrit monitoring to guide ultrafiltration.

resultsWe report five pediatric patients ranging in age from 7 days to 11 years and in size from 2.7 to 65 kg with hypoalbuminemia due to a variety of etiologies treated with slow continuous ultrafiltration with continuous hematocrit monitoring to guide ultrafiltration using the Aquadex device. Treatment allowed successful fluid removal in all cases, without hypotension or other hemodynamic complications.

conclusionsIn a variety of clinical circumstances and in patients from infants to adolescence, we report that patients with diuretic-resistant fluid overload can be treated with Aquadex using continuous hematocrit monitoring to guide management to allow fluid removal without hemodynamic instability or other complications. A higher resolution version of the Graphical abstract is available as Supplementary information.

Indexed as

Heart FailureHypoalbuminemiaWater-Electrolyte ImbalanceAdolescentChildEdemaHematocritHumansInfantUltrafiltrationDialysisFluid overloadHypoalbuminemiaNephroticUltrafiltration

Identifiers

PMID37661234
PMCPMC12231116
OpenAlexW4386399103

What OpenQuestion holds

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LicenceTDM
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.