Evidence map›Paper›PMID 37660541›Full record

ArticleParkinsonism & related disorders2023

Exploring mobility dysfunction in people with and without impaired cognition in Parkinson disease.

Natália Mariano Barboza, Martina Mancini, Suhaila Mahmoud Smaili, Fay B Horak, Patricia Carlson-Kuhta, Rosie Morris, Laurie A King

Abstract read
In one paragraph

Article in Parkinsonism & related disorders, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Natália Mariano BarbozaDepartment of Neurology, Neurofunctional Physiotherapy Group, State University of Londrina, Londrina, Brazil. Electronic address: natimbarboza@gmail.com.
Martina ManciniDepartment of Neurology, Balance Disorders Laboratory, Oregon Health & Science University, Portland, OR, USA.
Suhaila Mahmoud SmailiDepartment of Neurology, Neurofunctional Physiotherapy Group, State University of Londrina, Londrina, Brazil.
Fay B HorakDepartment of Neurology, Balance Disorders Laboratory, Oregon Health & Science University, Portland, OR, USA.
Patricia Carlson-KuhtaDepartment of Neurology, Balance Disorders Laboratory, Oregon Health & Science University, Portland, OR, USA.
Rosie MorrisInstitute of Neuroscience/Newcastle University Institute of Ageing, Clinical Ageing Research Unit, Campus for Ageing and Vitality Newcastle University, Newcastle upon Tyne, United Kingdom.
Laurie A KingDepartment of Neurology, Balance Disorders Laboratory, Oregon Health & Science University, Portland, OR, USA.

Funding

PERIPHERAL AND CENTRAL POSTURAL DISORDERS IN THE ELDERLYR01AG006457 · NIA · OREGON HEALTH & SCIENCE UNIVERSITY · PI HORAK, FAY BAHLING · 1986 to 2018
$5.2M
NIA NIH HHS R01 AG006457
6 · The paper itself

Abstract

introductionThe relationship between mobility and cognition has been studied in the aging population and associations have been also reported in people with Parkinson's disease (PD).

objectiveTo compare different aspects of gait and balance between individuals with PD who have normal cognition and those with impaired cognition, using both clinical and instrumented measures.

methodsOne-hundred forty-three participants with PD were divided into two groups: 1) normal cognition (n = 71) and 2) impaired cognition (n = 72) based on the Montreal Cognitive Assessment (MoCA) cut-off. Groups were compared using instrumented and clinical measures of gait and balance in the following domains: Sensory Orientation, Anticipatory Postural Adjustments, Automatic Postural Responses and Dynamic Balance for Gait. Instrumented measures were obtained via wearable sensors while performing eight different motor tasks and clinical measures were obtained with the Mini-BESTest.

resultsThe total Mini-BESTest score was not different between groups. However, the Dynamic Gait domain was worse in individuals with impaired cognition. Among the instrumented measures across domains, all significant group differences were in the Dynamic Gait domain, specifically, dual-task gait speed, dual-task stride length, stance time, and turn velocity.

conclusionsDynamic balance during gait was more impaired in people with PD who had abnormal cognition than those with normal cognition, for both clinical and instrumented measures. All other balance domains did not differ between groups, for both instrumented and clinical measures.

Indexed as

Cognitive DysfunctionParkinson DiseasePostural BalanceAgedAged, 80 and overFemaleGait Disorders, NeurologicHumansMaleMiddle AgedMobility LimitationBalanceCognitive disordersGaitParkinson's disease

Identifiers

PMID37660541
PMCPMC10591992

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.