Evidence map›Paper›PMID 37660399›Full record

ArticleThe British journal of radiology2023

Repeatability of quantitative individual lesion and total disease multiparametric whole-body MRI measurements in prostate cancer bone metastases.

Ricardo Donners, Antonio Candito, Matthew Blackledge, Mihaela Rata, Christina Messiou, Dow-Mu Koh, Nina Tunariu

Open access · hybridAbstract read
In one paragraph

Article in The British journal of radiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.8field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 7 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

Ricardo DonnersDepartment of Radiology, Royal Marsden Hospital, Sutton, United Kingdom.ORCID 0000-0002-1614-0521
Antonio CanditoCancer Research UK Cancer Imaging Centre, The Institute of Cancer Research, Sutton, United Kingdom.
Matthew BlackledgeCancer Research UK Cancer Imaging Centre, The Institute of Cancer Research, Sutton, United Kingdom.
Mihaela RataCancer Research UK Cancer Imaging Centre, The Institute of Cancer Research, Sutton, United Kingdom.
Christina MessiouDepartment of Radiology, Royal Marsden Hospital, Sutton, United Kingdom.
Dow-Mu KohDepartment of Radiology, Royal Marsden Hospital, Sutton, United Kingdom.
Nina TunariuDepartment of Radiology, Royal Marsden Hospital, Sutton, United Kingdom.
Institute of Cancer Research · GBUniversity Hospital of Basel · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTo assess the repeatability of quantitative multiparametric whole-body MRI (mpWB-MRI) parameters in advanced prostate cancer (APC) bone metastases.

methods1.5T MRI was performed twice on the same day in 10 APC patients. MpWB-MRI-included diffusion weighted imaging (DWI) and

resultsSeventy-three individual targets (median MD 26 mm) were included. Lesion mean ADC RC was 12.5%, mean b900 SI RC 137%, normalised mean b900 SI RC 110%, rFF% RC 3.2 and target MD RC 5.5 mm (16.3%). Patient target lesion average mean ADC RC was 6.4%, b900 SI RC 104% and normalised mean b900 SI RC 39.6%. Target average rFF% RC was 1.8, average MD RC 1.3 mm (4.8%). tDV segmentation RC was 6.4% and mean gADC RC 5.3%.

conclusionsAPC bone metastases' ADC, rFF% and maximum diameter, tDV and gADC show good repeatability. ADVANCES IN KNOWLEDGE: APC bone metastases' mean ADC and rFF% measurements of single lesions and global disease volumes are repeatable, supporting their potential role as quantitative biomarkers in metastatic bone disease.

Indexed as

Bone NeoplasmsMultiparametric Magnetic Resonance ImagingProstatic NeoplasmsDiffusion Magnetic Resonance ImagingHumansMagnetic Resonance ImagingMale

Identifiers

PMID37660399
PMCPMC10607420
OpenAlexW4386397719

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.