Evidence map›Paper›PMID 37660344›Full record

ArticleEuropean geriatric medicine2024

Potential confounders of the obesity paradox in older patients following transcatheter aortic valve replacement.

Satoshi Higuchi, Hidenari Matsumoto, Ryota Masaki, Takaho Hirano, Shiori Fuse, Hiroki Tanisawa, Tomoaki Masuda, Yasuhide Mochizuki, Kazuto Maruta, Seita Kondo and 3 more

Abstract read
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In one paragraph

Article in European geriatric medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
1.3field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 6 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Your CT scans are hiding crucial TAVI survival data: Are you looking?American heart journal plus : cardiology research and practice · 2025
    Article
  5. Article
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 2 institutions in 1 country.

Satoshi HiguchiDivision of Cardiology, Department of Medicine, Showa University School of Medicine, 1-5-8 Hatanodai, Shinagawa, Tokyo, 142-8555, Japan. sahiguchi-circ@umin.ac.jp.ORCID 0000-0002-7914-8256
Hidenari MatsumotoDivision of Cardiology, Department of Medicine, Showa University School of Medicine, 1-5-8 Hatanodai, Shinagawa, Tokyo, 142-8555, Japan.
Ryota MasakiDivision of Cardiology, Department of Medicine, Showa University School of Medicine, 1-5-8 Hatanodai, Shinagawa, Tokyo, 142-8555, Japan.
Takaho HiranoDepartment of Radiological Technology, Showa University Hospital, Tokyo, Japan.
Shiori FuseDivision of Cardiology, Department of Medicine, Showa University School of Medicine, 1-5-8 Hatanodai, Shinagawa, Tokyo, 142-8555, Japan.
Hiroki TanisawaDivision of Cardiology, Department of Medicine, Showa University School of Medicine, 1-5-8 Hatanodai, Shinagawa, Tokyo, 142-8555, Japan.
Tomoaki MasudaDivision of Cardiovascular Surgery, Department of Surgery, Showa University School of Medicine, Tokyo, Japan.
Yasuhide MochizukiDivision of Cardiology, Department of Medicine, Showa University School of Medicine, 1-5-8 Hatanodai, Shinagawa, Tokyo, 142-8555, Japan.
Kazuto MarutaDivision of Cardiovascular Surgery, Department of Surgery, Showa University School of Medicine, Tokyo, Japan.
Seita KondoDivision of Cardiology, Department of Medicine, Showa University School of Medicine, 1-5-8 Hatanodai, Shinagawa, Tokyo, 142-8555, Japan.
Tadashi OmotoDivision of Cardiovascular Surgery, Department of Surgery, Showa University School of Medicine, Tokyo, Japan.
Atsushi AokiDivision of Cardiovascular Surgery, Department of Surgery, Showa University School of Medicine, Tokyo, Japan.
Toshiro ShinkeDivision of Cardiology, Department of Medicine, Showa University School of Medicine, 1-5-8 Hatanodai, Shinagawa, Tokyo, 142-8555, Japan.
Showa University · JPShowa University Hospital · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeA higher body mass index (BMI) is associated with lower mortality in older patients following transcatheter aortic valve replacement (TAVR) for severe aortic valve stenosis. The current study aimed to investigate potential confounders of association between BMI and prognosis.

methodsThe retrospective single-center study included consecutive patients following TAVR and excluded those in whom subcutaneous fat accumulation (SFA), visceral fat accumulation (VFA), and major psoas muscle (MPM) volume were not assessed by computed tomography. Cachexia was defined as a combination of BMI < 20 kg/m

resultsAfter 2 patients were excluded, 234 (age, 86 ± 5 years; male, 77 [33%]; BMI, 22.4 ± 3.8 kg/m

conclusionsAssociation of higher BMI with lower mortality may be confounded by SFA in older patients following TAVR. Cachexia might reflect higher mortality in patients with lower BMI.

Indexed as

Transcatheter Aortic Valve ReplacementAgedAged, 80 and overCachexiaHumansMaleObesity ParadoxRetrospective StudiesRisk FactorsTreatment OutcomeBody mass indexCachexiaObesity paradoxSubcutaneous fatTranscatheter aortic valve replacement

Identifiers

PMID37660344
OpenAlexW4386400122

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.