Evidence map›Paper›PMID 37660324›Full record

ArticleJournal of chemical information and modeling2024

Integrating Mechanistic and Toxicokinetic Information in Predictive Models of Cholestasis.

Pablo Rodríguez-Belenguer, Victor Mangas-Sanjuan, Emilio Soria-Olivas, Manuel Pastor

Abstract read
In one paragraph

Article in Journal of chemical information and modeling, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Pablo Rodríguez-BelenguerResearch Programme on Biomedical Informatics (GRIB), Department of Medicine and Life Sciences, Universitat Pompeu Fabra, Hospital del Mar Medical Research Institute, 08003 Barcelona, Spain.ORCID 0000-0001-5270-7452
Victor Mangas-SanjuanDepartment of Pharmacy and Pharmaceutical Technology and Parasitology, Universitat de València, 46100 Valencia, Spain.
Emilio Soria-OlivasIDAL, Intelligent Data Analysis Laboratory, ETSE, Universitat de València, 46100 Valencia, Spain.ORCID 0000-0002-9148-8405
Manuel PastorResearch Programme on Biomedical Informatics (GRIB), Department of Medicine and Life Sciences, Universitat Pompeu Fabra, Hospital del Mar Medical Research Institute, 08003 Barcelona, Spain.ORCID 0000-0001-8850-1341

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Drug development involves the thorough assessment of the candidate's safety and efficacy.

Indexed as

CholestasisQuantitative Structure-Activity RelationshipAnimalsDrug DevelopmentToxicokinetics

Identifiers

PMID37660324
PMCPMC11005038

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.