ArticleActa neurochirurgica2023
The clinical course and outcomes of non-aneurysmal subarachnoid hemorrhages in a single-center retrospective study.
Article in Acta neurochirurgica, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 16 papers.
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Who cites it
16 citing papers in PubMed.
- Serum S100B and Clinical Outcomes After Spontaneous Subarachnoid Hemorrhage: A Prospective Observational Study.Molecular neurobiology · 2026Observational
- Blood C-reactive protein and white blood cells trajectories and associations with clinical parameters and complications in the acute phase after subarachnoid hemorrhage.Acta neurochirurgica · 2026Article
- Clinical and epidemiological comparison between perimesencephalic and non-perimesencephalic, non-aneurysmal subarachnoid hemorrhage: a single-center cohort study from a referral center in a developing country.Arquivos de neuro-psiquiatria · 2026Article
- Non-Aneurysmal Subarachnoid Hemorrhage in a Patient With Type 1 Diabetes Mellitus: A Case Report.Cureus · 2026Article
- Delayed identification and treatment of a cervicomedullary spinal vascular lesion following angiogram-negative, high-grade subarachnoid hemorrhage: illustrative case.Journal of neurosurgery. Case lessons · 2026Article
- Functional outcome, return to work and quality of life in patients with non-aneurysmal subarachnoid hemorrhage.European stroke journal · 2026Article
- Perimesencephalic non-aneurysmal subarachnoid hemorrhage: is there a need for repeat digital subtraction angiography?Neuroradiology · 2025Article
- Volumetric Assessment of Perimesencephalic Subarachnoid Hemorrhage.Neurology and therapy · 2025Article
- When Guidelines Fail: A Case Report of Rule-Negative Traumatic Subarachnoid Hemorrhage From a Contrecoup Mechanism.Cureus · 2025Article
- Functional outcome, return to work and quality of life in patients with non-aneurysmal subarachnoid hemorrhage.European stroke journal · 2025Article
- Perimesencephalic Subarachnoid Hemorrhage Bleeding Patterns Are Not Always Benign: Prognostic Impact of an Aneurysmal Pathology.Biomedicines · 2025Article
- Exclusion criteria in randomized clinical trials of subarachnoid hemorrhage.Neurosurgical review · 2025Article
- Perimesencephalic Subarachnoid Hemorrhage Is Not Always a Benign Condition: Hemorrhage Volume as a Predictor for Complications and Clinical Outcome.Biomedicines · 2025Article
- Article
- Post-Thrombectomy Subarachnoid Hemorrhage: Incidence, Predictors, Clinical Relevance, and Effect Modulators.Diagnostics (Basel, Switzerland) · 2024Article
- Stability of infundibular dilatations: a single center follow-up study and systematic review of the literature.Acta neurochirurgica · 2024Article
Corrections and comments
- Erratum issued
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundNon-aneurysmal subarachnoid hemorrhages (SAHs) are thought to have a benign clinical course compared to aneurysmal SAHs. The aim of this study is to report the clinical course and outcomes of non-aneurysmal SAHs in a large single-center study.
methodsThe patients with non-aneurysmal SAHs were screened from Tampere University Hospital from 2005 to 2020. The clinical data were collected from the patient's medical records and from the imaging studies. The primary interest was the neurological outcome assessed by dichotomized GOS at 2 months. Multivariable logistic regression was used to study the factors associated with unfavorable outcome.
resultsWe found 216 non-aneurysmal SAHs in 214 patients (2 patients with > 1 bleed). Ninety-seven percent of patients with a typical perimesencephalic bleeding pattern SAH (PSAH) (75/77) had a favorable outcome, while 86% of patients with non-perimesencephalic SAH (NPSAH) had a favorable outcome (84/98). In a multivariable logistic regression analysis, loss of consciousness (LOC) (aOR 214.67, 95% CI 17.62-2615.89) and Fisher grade 4 bleeding pattern (aOR 23.32, 95% CI 1.40-387.98) were associated with increased risk for unfavorable outcome (GOS 1-3). Vasospasm was seen in 20% of non-aneurysmal SAH patients, hydrocephalus in 17%, and 13% needed ventriculostomy.
conclusionsNon-aneurysmal SAH seems to have a good prognosis for majority of patients, especially for patients with a PSAH. Non-aneurysmal SAH patients are however affected by vasospasm and hydrocephalus and have similar risk factors for poor outcome as patients with aneurysmal SAH. This suggests that it is the severity of the bleed rather than the etiology that associates with poor outcome.
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