Evidence map›Paper›PMID 37658890›Full record

ArticleEuropean radiology2024

Deep learning-based segmentation of whole-body fetal MRI and fetal weight estimation: assessing performance, repeatability, and reproducibility.

Bella Specktor-Fadida, Daphna Link-Sourani, Aviad Rabinowich, Elka Miller, Anna Levchakov, Netanell Avisdris, Liat Ben-Sira, Liran Hiersch, Leo Joskowicz, Dafna Ben-Bashat

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Article in European radiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 1 synthesis or guideline pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Bella Specktor-FadidaSchool of Computer Science and Engineering, The Hebrew University of Jerusalem, Jerusalem, Israel. bella.specktor@mail.huji.ac.il.ORCID http://orcid.org/0000-0002-5668-0303
Daphna Link-SouraniSagol Brain Institute, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel.
Aviad RabinowichSagol Brain Institute, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel.
Elka MillerDepartment of Medical Imaging, The Hospital for Sick Children, University of Toronto, Toronto, Canada.ORCID http://orcid.org/0000-0003-1075-5952
Anna LevchakovSagol Brain Institute, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel.
Netanell AvisdrisSchool of Computer Science and Engineering, The Hebrew University of Jerusalem, Jerusalem, Israel.ORCID http://orcid.org/0000-0002-0719-1327
Liat Ben-SiraFaculty of Medicine, Tel Aviv University, Tel Aviv, Israel.
Liran HierschFaculty of Medicine, Tel Aviv University, Tel Aviv, Israel.
Leo JoskowiczSchool of Computer Science and Engineering, The Hebrew University of Jerusalem, Jerusalem, Israel.
Dafna Ben-BashatSagol Brain Institute, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel. dafnab@tlvmc.gov.il.

Funding

Israel Innovation Authority 63418Israel Innovation Authority 72126
6 · The paper itself

Abstract

objectivesTo develop a deep-learning method for whole-body fetal segmentation based on MRI; to assess the method's repeatability, reproducibility, and accuracy; to create an MRI-based normal fetal weight growth chart; and to assess the sensitivity to detect fetuses with growth restriction (FGR).

methodsRetrospective data of 348 fetuses with gestational age (GA) of 19-39 weeks were included: 249 normal appropriate for GA (AGA), 19 FGR, and 80 Other (having various imaging abnormalities). A fetal whole-body segmentation model with a quality estimation module was developed and evaluated in 169 cases. The method was evaluated for its repeatability (repeated scans within the same scanner, n = 22), reproducibility (different scanners, n = 6), and accuracy (compared with birth weight, n = 7). A normal MRI-based growth chart was derived.

resultsThe method achieved a Dice = 0.973, absolute volume difference ratio (VDR) = 1.8% and VDR mean difference = 0.75% ([Formula: see text]: - 3.95%, 5.46), and high agreement with the gold standard. The method achieved a repeatability coefficient = 4.01%, ICC = 0.99, high reproducibility with a mean difference = 2.21% ([Formula: see text]: - 1.92%, 6.35%), and high accuracy with a mean difference between estimated fetal weight (EFW) and birth weight of - 0.39% ([Formula: see text]: - 8.23%, 7.45%). A normal growth chart (n = 246) was consistent with four ultrasound charts. EFW based on MRI correctly predicted birth-weight percentiles for all 18 fetuses ≤ 10

conclusionsThe proposed method for automatic MRI-based EFW demonstrated high performance and sensitivity to identify FGR fetuses. CLINICAL RELEVANCE STATEMENT: Results from this study support the use of the automatic fetal weight estimation method based on MRI for the assessment of fetal development and to detect fetuses at risk for growth restriction. KEY POINTS: • An AI-based segmentation method with a quality assessment module for fetal weight estimation based on MRI was developed, achieving high repeatability, reproducibility, and accuracy. • An MRI-based fetal weight growth chart constructed from a large cohort of normal and appropriate gestational-age fetuses is proposed. • The method showed a high sensitivity for the diagnosis of small fetuses suspected of growth restriction.

Indexed as

Deep LearningFetal WeightBirth WeightFemaleFetal Growth RetardationFetusGestational AgeHumansInfantInfant, NewbornInfant, Small for Gestational AgeMagnetic Resonance ImagingPregnancyReproducibility of ResultsRetrospective StudiesUltrasonography, PrenatalDeep learningFetal growth restrictionFetal weightGrowth chartMagnetic resonance imaging

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.