Observational studyLung2023
Baseline Cohort Profile of the Korean Chronic Cough Registry: A Multicenter, Prospective, Observational Study.
Observational study in Lung, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
26 citing papers in PubMed.
- Trial
- Age-Dependent Role of Cough Hypersensitivity in Transition to Refractory Chronic Cough.Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology · 2026Article
- Challenges and Burdens in Refractory Chronic Cough: Patients' and Physicians' Perspectives.Pulmonary therapy · 2026Review
- Prevalence and associated factors of cough syncope in patients with chronic cough: a multicentre prospective study.ERJ open research · 2026Article
- Article
- Article
- KAAACI Consensus Document on the Goals and Standards of Chronic Cough Clinics in Korea: A Delphi Study.Allergy, asthma & immunology research · 2026Article
- Clarifying Terminology in Chronic Cough: The Evolving Role of Cough Hypersensitivity Syndrome.The clinical respiratory journal · 2026Review
- Observational
- Differences in Causes, Severity, and Treatment Outcomes Between Women and Men with Chronic Cough.Advances in respiratory medicine · 2026Article
- RFC1 Repeat Expansion in Chronic Cough: Findings From the Korean Chronic Cough Registry.Allergy, asthma & immunology research · 2026Article
- Quality of life associated with chronic cough in the multinational Burden of Obstructive Lung Disease study: a cross-sectional study.ERJ open research · 2025Article
- Unmet need for biomarkers in chronic cough: a review of current challenges and future directions.ERJ open research · 2025Review
- Redefining chronic cough as a disease: why patient registries matter.ERJ open research · 2025Article
- The NEuroCOUGH Chronic Cough Registry: a protocol for a pan-European observational study.ERJ open research · 2025Article
- Association of throat sensation severity with quality of life in patients with chronic cough.Journal of thoracic disease · 2025Article
- Observational
- Article
- Treatable traits in chronic cough: a prospective evaluation for predicting cough persistence.ERJ open research · 2025Article
- How Will a Treatable Traits Approach Reshape Clinical Practice in Chronic Cough?Allergy, asthma & immunology research · 2025Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
24 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeThe Korean Chronic Cough Registry study was initiated to characterize patients with chronic cough (CC) and investigate their outcomes in real-world clinical practice. This report aims to describe the baseline cohort profile and study protocols.
methodsThis multicenter, prospective observational cohort study included newly referred CC patients and those already being treated for refractory or unexplained chronic cough (RUCC). Cough status was assessed using a visual analog scale, the Leicester Cough Questionnaire (LCQ), and the Cough Hypersensitivity Questionnaire (CHQ).
resultsA total of 610 patients (66.9% women; median age 59.0 years) were recruited from 18 centers, with 176 being RUCC patients (28.9%). The median age at CC onset was 50.1 years, and 94.4% had adult-onset CC (≥ 19 years). The median cough duration was 4 years. Compared to newly referred CC patients, RUCC patients had a longer cough duration (6.0 years vs. 3.0 years) but had fewer symptoms and signs suggesting asthma, rhinosinusitis, or gastroesophageal acid reflux disease. Subjects with RUCC had lower LCQ scores (10.3 ± 3.3 vs. 11.6 ± 3.6; P < 0.001) and higher CHQ scores (9.1 ± 3.9 vs. 8.4 ± 4.1; P = 0.024). There were no marked differences in the characteristics of cough between refractory chronic cough and unexplained chronic cough.
conclusionsChronic cough typically develops in adulthood, lasting for years. Cough severity and quality of life impairment indicate the presence of unmet clinical needs and insufficient cough control in real-world clinical practice. Longitudinal follow-up is warranted to investigate the natural history and treatment outcomes.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.