Evidence map›Paper›PMID 37658750›Full record

ArticleAge and ageing2023

Breathlessness limiting exertion in very old adults: findings from the Newcastle 85+ study.

Miriam J Johnson, Lukas Pitel, David C Currow, Cynthia Forbes, Ireneous Soyiri, Louise Robinson

Open access · bronzeAbstract read
In one paragraph

Article in Age and ageing, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 2 countries.

Miriam J JohnsonWolfson Palliative Care Research Centre, Hull York Medical School, University of Hull, Hull, UK.
Lukas PitelHull Health Trials Unit, Hull York Medical School, University of Hull, Hull, UK.
David C CurrowDepartment of Medicine and Health, University of Wollongong, Wollongong, NSW, Australia.
Cynthia ForbesWolfson Palliative Care Research Centre, Hull York Medical School, University of Hull, Hull, UK.
Ireneous SoyiriHull York Medical School, University of Hull, Hull, UK.
Louise RobinsonPopulation Health Sciences Institute, Newcastle University, Newcastle upon Tyne, UK.
Hull York Medical School · GBUniversity of Hull · GBNewcastle University · GBUniversity of Wollongong · AU

Funding

Biotechnology and Biological Sciences Research CouncilBritish Heart FoundationMedical Research Council
6 · The paper itself

Abstract

introductionLong-term breathlessness is more common with age. However, in the oldest old (>85 years), little is known about the prevalence, or impact of breathlessness. We estimated breathlessness limiting exertion prevalence and explored (i) associated characteristics; and (ii) whether breathlessness limiting exertion explains clinical and social/functional outcomes.

methodsHealth and socio-demographic characteristics were extracted from the Newcastle 85+ Study cohort. Phase 1 (baseline) and follow-up data (18 months, Phase 2; 36 months, Phase 3; 60 months, Phase 4 after baseline) were examined using descriptive statistics and cross-sectional regression models.

resultsEight hundred seventeen participants provided baseline breathlessness data (38.2% men; mean 84.5 years; SD 0.4). The proportions with any limitation of exertion, or severe limitation by breathlessness were 23% (95% confidence intervals (CIs) 20-25%) and 9% (95%CIs 7-11%) at baseline; 20% (16-25%) and 5% (3-8%) at Phase 4. Having more co-morbidities (odds ratio (OR) 1.34, 1.18-1.54; P < 0.001), or self-reported respiratory (OR 1.88, 1.25-2.82; P = 0.003) or cardiovascular disease (OR 2.38, 1.58-3.58; P < 0.001) were associated with breathlessness limiting exertion. Breathlessness severely limiting exertion was associated with poorer self-rated health (OR 0.50, 029-0.86; P = 0.012), depression (beta-coefficient 0.11, P = 0.001), increased primary care contacts (beta-co-efficient 0.13, P = 0.001) and number of nights in hospital (OR 1.81; 1.02-3.20; P = 0.042).

conclusionsBreathlessness limiting exertion appears to become less prevalent over time due to death or withdrawal of participants with cardio-respiratory illness. Breathlessness severely limiting exertion had a wide range of service utilisation and wellbeing impacts.

Indexed as

DyspneaPhysical ExertionAged, 80 and overCardiovascular DiseasesCross-Sectional StudiesFemaleHospitalsHumansMaleagedbreathlessnessdyspnoeaolder adultolder peopleprevalence

Identifiers

PMID37658750
PMCPMC10474592
OpenAlexW4386393524

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.