ArticleAlzheimer's & dementia : the journal of the Alzheimer's Association2024
Trajectories of cognitive and perceived functional decline in people with dementia: Findings from the IDEAL programme.
Article in Alzheimer's & dementia : the journal of the Alzheimer's Association, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed.
- Prognostic factors for functional decline in community-dwelling older adults with dementia: a systematic review and meta-analysis.European geriatric medicine · 2026Review
- Predicting rates of cognitive and functional decline in Alzheimer's disease and mild cognitive impairment.Communications medicine · 2026Article
- Waking up to the truth: Associations between sleep disorders and multidomain functional outcomes in Alzheimer's disease.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2026Article
- Chronic pain and subjective memory problems are dynamic risk factors for functional decline: An ACTIVE longitudinal study.Experimental gerontology · 2025Article
- Interpreting Addenbrooke's Cognitive Examination-III Scores in Dementia: Performance Distributions and Clinically Meaningful Change.European journal of neurology · 2025Article
- Healthcare Awareness Profile Interview: Development of a new evidence-based brief clinical tool to assess awareness in people with dementia.Neuropsychological rehabilitation · 2025Article
- Article
- Differences in trajectories of quality of life according to type of dementia: 6-year longitudinal findings from the IDEAL programme.BMC medicine · 2024Article
- Trajectories of cognitive and perceived functional decline in people with dementia: Findings from the IDEAL programme.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2024Article
- Resilience in caregivers of people with mild-to-moderate dementia: findings from the IDEAL cohort.BMC geriatrics · 2023Article
- Time saved in activities of daily living and whole-brain volume: Post hoc analysis of a randomized feasibility trial of gamma oscillation treatment in participants with mild or moderate Alzheimer's disease.Alzheimer's & dementia (New York, N. Y.)Article
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Abstract
introductionImpaired cognition and instrumental activities of daily living (iADL) are key diagnostic features of dementia; however, few studies have compared trajectories of cognition and iADL.
methodsParticipants from the IDEAL study comprised 1537, 1183, and 851 people with dementia, and 1277, 977, and 749 caregivers at baseline, 12 and 24 months, respectively. Addenbrooke's Cognitive Examination-III and Functional Activities Questionnaire were used to measure cognition and iADL, respectively. Scores were converted to deciles.
resultsSelf-rated iADL declined on average by -0.08 (-0.25, 0.08) decile points per timepoint more than cognition. Informant-rated iADL declined on average by -0.31 (-0.43, -0.18) decile points per timepoint more than cognition. DISCUSSION: Cognition and self-rated iADL declined at a similar rate. Informant-rated iADL declined at a significantly greater rate than cognition. Therefore, either cognition and perceived iADL decline at different rates or informants overestimate increasing iADL difficulties compared to both cognition and self-ratings. HIGHLIGHTS: Self-ratings of the degree of functional difficulties were consistent with cognition Decline in self-rated everyday activities was consistent with cognitive decline Informant-ratings of everyday activities declined more than cognition.
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