Evidence map›Paper›PMID 37658738›Full record

Trial reportInternational journal of stroke : official journal of the International Stroke Society2024

Secondary prevention of stroke. A telehealth-delivered physical activity and diet pilot randomized trial (ENAbLE-pilot).

Coralie English, Emily R Ramage, John Attia, Julie Bernhardt, Billie Bonevski, Meredith Burke, Margaret Galloway, Graeme J Hankey, Heidi Janssen, Richard Lindley and 7 more

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in International journal of stroke : official journal of the International Stroke Society, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed.

  1. Trial
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  3. Mobile health delivered physical activity after mild stroke or transient ischemic attack: Is it feasible and acceptable?International journal of stroke : official journal of the International Stroke Society · 2025
    Trial
  4. Trial
  5. Review
  6. Article
  7. Review
  8. Article
  9. Review
  10. Article
  11. Article
  12. Article
  13. Article
  14. Current Trends in Virtual Exercise Interventions Among People With Disabilities: A Scoping Review.Archives of rehabilitation research and clinical translation · 2024
    Review
  15. Article
  16. Article
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Coralie EnglishSchool of Health Sciences, University of Newcastle, Newcastle, NSW, Australia.ORCID 0000-0001-5910-7927
Emily R RamageSchool of Health Sciences, University of Newcastle, Newcastle, NSW, Australia.ORCID 0000-0002-0599-7028
John AttiaSchool of Medicine and Public Health, University of Newcastle, Newcastle, NSW, Australia.
Julie BernhardtThe Florey Institute, Melbourne, VIC, Australia.ORCID 0000-0002-2787-8484
Billie BonevskiFlinders Health and Medical Research Institute, College of Medicine and Public Health, Flinders University, Adelaide, SA, Australia.
Meredith BurkeHeart and Stroke Program, Hunter Medical Research Institute, Newcastle, NSW, Australia.
Margaret GallowaySchool of Health Sciences, University of Newcastle, Newcastle, NSW, Australia.
Graeme J HankeyMedical School, Faculty of Health and Medical Sciences, The University of Western Australia, Perth, WA, Australia.ORCID 0000-0002-6044-7328
Heidi JanssenSchool of Health Sciences, University of Newcastle, Newcastle, NSW, Australia.
Richard LindleyCentre of Research Excellence to Accelerate Stroke Trial Innovation and Translation, University of Sydney, Sydney, NSW, Australia.ORCID 0000-0002-0104-5679
Elizabeth LynchCaring Futures Institute, Flinders University, Adelaide, SA, Australia.
Chris OldmeadowHunter Medical Research Institute, Newcastle, NSW, Australia.
Catherine M SaidPhysiotherapy, Western Health, St Albans, VIC, Australia.
Neil J SprattHeart and Stroke Program, Hunter Medical Research Institute, Newcastle, NSW, Australia.
Karly ZachariaSchool of Health Sciences, University of Newcastle, Newcastle, NSW, Australia.ORCID 0000-0002-4864-2585
Lesley MacDonald-WicksSchool of Health Sciences, University of Newcastle, Newcastle, NSW, Australia.
Amanda PattersonSchool of Health Sciences, University of Newcastle, Newcastle, NSW, Australia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundImproving physical activity levels and diet quality are important for secondary stroke prevention.

aimTo test the feasibility and safety of 6-month, co-designed telehealth-delivered interventions to increase physical activity and improve diet quality.

methodsA 2 × 2 factorial trial (physical activity (PA); diet (DIET); PA + DIET; control) randomized, open-label, blinded endpoint trial. Primary outcomes were feasibility and safety. Secondary outcomes included stroke risk factors (blood pressure, self-report PA (International Physical Activity Questionnaire (IPAQ)) and diet quality (Australian Recommended Food Score (ARFS)), and quality of life. Between-group differences were analyzed using linear-mixed models.

resultsOver 23 months, 99 people were screened for participation and 40 (40%) randomized (3 months to 10 years post-stroke, mean age 59 (16) years). Six participants withdrew, and an additional five were lost to follow-up. Fifteen serious adverse events were reported, but none were deemed definitely or probably related to the intervention. Median attendance was 32 (of 36) PA sessions and 9 (of 10) DIET sessions. The proportion of missing primary outcome data (blood pressure) was 3% at 3 months, 11% at 6 months, and 14% at 12 months. Between-group 95% confidence intervals showed promising, clinically relevant differences in support of the interventions across the range of PA, diet quality, and blood pressure outcomes.

conclusionOur telehealth PA and diet interventions were safe and feasible and may have led to significant behavior change.

trial registrationACTRN12620000189921.

Indexed as

StrokeTelemedicineAdultAgedAustraliaDietExerciseHumansMiddle AgedPilot ProjectsQuality of LifeSecondary Preventionblood pressuredietPhysical activitypilot trialquality of lifetelehealth

Identifiers

PMID37658738
PMCPMC10811968

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.