Evidence map›Paper›PMID 37658450›Full record

ArticleMalaria journal2023

Malaria in adults after the start of Covid-19 pandemic: an analysis of admission trends, demographics, and outcomes in a tertiary hospital in the Gambia.

Sheikh Omar Bittaye, Abubacarr Jagne, Lamin E S Jaiteh, Alfred Amambua-Ngwa, Abdul Karim Sesay, Bertha Ekeh, Behzad Nadjm, Williams Estrada Ramirez, Asmell Ramos, Basil Okeahialam and 3 more

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Article in Malaria journal, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Sheikh Omar Bittaye *Internal Medicine Department, Edward Francis Small Teaching Hospital, Banjul, The Gambia. sobittaye@utg.edu.gm.
Abubacarr JagneInternal Medicine Department, Edward Francis Small Teaching Hospital, Banjul, The Gambia.
Lamin E S JaitehInternal Medicine Department, Edward Francis Small Teaching Hospital, Banjul, The Gambia.
Alfred Amambua-NgwaMedical Research Council, The London School of Hygiene and Tropical Medicine, Fajara, The Gambia.
Abdul Karim SesayMedical Research Council, The London School of Hygiene and Tropical Medicine, Fajara, The Gambia.
Bertha EkehInternal Medicine Department, Edward Francis Small Teaching Hospital, Banjul, The Gambia.
Behzad NadjmMedical Research Council, The London School of Hygiene and Tropical Medicine, Fajara, The Gambia.
Williams Estrada RamirezInternal Medicine Department, Edward Francis Small Teaching Hospital, Banjul, The Gambia.
Asmell RamosInternal Medicine Department, Edward Francis Small Teaching Hospital, Banjul, The Gambia.
Basil OkeahialamInternal Medicine Department, Edward Francis Small Teaching Hospital, Banjul, The Gambia.
Emmanuel EffaInternal Medicine Department, Edward Francis Small Teaching Hospital, Banjul, The Gambia.
Ousman NyanInternal Medicine Department, Edward Francis Small Teaching Hospital, Banjul, The Gambia.
Ramou NjieInternal Medicine Department, Edward Francis Small Teaching Hospital, Banjul, The Gambia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundMalaria remains a major public health concern in The Gambia. The study assessed the trend of malaria admissions and outcome of adult patients admitted after the start of the COVID-19 pandemic in a tertiary hospital in The Gambia.

methodsThis was a retrospective hospital-based study and data was collected from the 18th October 2020 to 28th February 2023. Demographic data, clinical features, investigations, treatment, and outcomes were recorded.

resultsA total of 499 malaria cases were admitted to the hospital over the 29 months of the study period. Data from 320 (67.2% of the total cases) adult patients admitted into the internal medicine department were analysed. The median age was 22 years, range (15-90) and 189 (59.1%) cases were youth with a youth (15-24 years) to older adult (> 24 years) ratio of 1.4:1. The majority of the patients were male 199 (62.2) with a male to female ratio of 1.6:1. The total number of malaria cases admitted into the internal medicine department increased from 103 cases in 2021 to 182 cases in 2022and admission peaked in November in both years. The total number of admitted malaria cases during the peak of the malaria season also increased from 92 patients between September 2021 and December 2021 to 132 patients from September 2022 to December 2022.There was also an increase in both severe and uncomplicated malaria during the same period. The total mortality was 31 (9.7%) and the rate was similar in 2021 9 (8.7%) and 2022 15 (8.4%). Patients with impaired consciousness were more likely to die when compared to those without impaired consciousness [19 (23.6%) vs 12 (5%), p  ≤ 0.001]. Patients with acute kidney injury were also more likely to die when compared with those without acute kidney injury [10 (20.4%) vs 15 (7.7%), p = 0.009].

conclusionThe findings show an emerging and consistent trend of malaria admissions and the outcome in the youth and older adult population after the start of the COVID-19 pandemic in The Gambia. This, therefore, suggests the need for the implementation of targeted malaria prevention interventions in this population to further prevent the spread of the disease to the more vulnerable population.

Indexed as

Acute Kidney InjuryCOVID-19MalariaAdolescentAdultAgedAged, 80 and overDemographyFemaleGambiaHumansMaleMiddle AgedPandemicsRetrospective StudiesTertiary Care CentersAdmissionAdultsCOVID-19GambiaMalariaOutcomeTrend

Identifiers

PMID37658450
PMCPMC10474732

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.