Evidence map›Paper›PMID 37658425›Full record

ArticleVeterinary research2023

Genomic molecular epidemiology of carbapenemase-producing Escherichia coli ST410 isolates by complete genome analysis.

Su Min Kyung, Junho Lee, Eun-Seo Lee, Cheol-Yong Hwang, Han Sang Yoo

Open access · goldAbstract read
In one paragraph

Article in Veterinary research, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.3field-weighted citation impact, top 53% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 2 countries.

Su Min KyungDepartment of Infectious Diseases, College of Veterinary Medicine, Seoul National University, Seoul, Republic of Korea.
Junho LeeDepartment of Infectious Diseases, College of Veterinary Medicine, Seoul National University, Seoul, Republic of Korea.
Eun-Seo LeeDepartment of Infectious Diseases, College of Veterinary Medicine, Seoul National University, Seoul, Republic of Korea.
Cheol-Yong HwangDepartment of Veterinary Dermatology, College of Veterinary Medicine, Seoul National University, Seoul, Republic of Korea.
Han Sang YooDepartment of Infectious Diseases, College of Veterinary Medicine, Seoul National University, Seoul, Republic of Korea. yoohs@snu.ac.kr.ORCID http://orcid.org/0000-0003-0548-0835
Seoul National University · KR

Funding

National Research Foundation of Korea NRF- 2020R1A2C200879414
6 · The paper itself

Abstract

The circulation of carbapenemase-producing Escherichia coli (CPEC) in our society is a serious concern for vulnerable patients in nosocomial environments. However, the genomic epidemiology of the circulation of CPEC bacteria among companion animals remains largely unknown. In this study, epidemiological analysis was conducted using complete genome identification of CPEC ST410 isolates obtained from companion animals. To estimate the genomic distance and relatedness of the isolates, a total of 37 whole-genome datasets of E. coli ST410 strains were downloaded and comparatively analysed. As a result of the analysis, the genomic structure of the chromosomes and plasmids was identified, revealing the genomic positions of multiple resistance and virulence genes. The isolates in this study were grouped into the subclade H24/RxC, with fimH24, and substituted quinolone resistance-determining regions (QRDRs) and multiple beta-lactamases, including extended-spectrum β-lactamase (ESBL) and carbapenemase. In addition, the in silico comparison of the whole-genome datasets revealed unidentified ST410 H24/Rx subgroups, including either high pathogenicity islands (HPIs) or H21 serotypes. Considering the genetic variations and resistance gene dissemination of the isolates carried by companion animals, future approaches for preventive measurement must include the "One Health" perspective for public health in our society.

Indexed as

Escherichia coliGenomicsAnimalsBacterial Proteinsbeta-LactamasesMolecular EpidemiologyBacterial Proteinsbeta-LactamasescarbapenemasecarbapenemaseEnterobacteralesepidemiologyEscherichia colimetallo-β-lactamaseMinIONNDM-5NGSOne HealthST410

Identifiers

PMID37658425
PMCPMC10472685
OpenAlexW4386385526

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.