Evidence map›Paper›PMID 37658408›Full record

ArticleJournal of neuroengineering and rehabilitation2023

Effects of a soft robotic exosuit on the quality and speed of overground walking depends on walking ability after stroke.

Lizeth H Sloot, Lauren M Baker, Jaehyun Bae, Franchino Porciuncula, Blandine F Clément, Christopher Siviy, Richard W Nuckols, Teresa Baker, Regina Sloutsky, Dabin K Choe and 4 more

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in Journal of neuroengineering and rehabilitation, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07218094 (Neuromechanical Mechanisms of Exosuit-assisted Gait Rehabilitation After Stroke), which is not on this map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
4.0field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07218094 naenrolling by invitationnot on this mapstarted 2025, after this paper: background citation

Neuromechanical Mechanisms of Exosuit-assisted Gait Rehabilitation After Stroke

TypeinterventionalSponsorBoston University Charles River CampusRan2025 to 2027Enrolled22ConditionsStrokeArmsWalking with robotic ankle assistance
3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it, 29 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Review
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 5 institutions in 3 countries.

Lizeth H SlootHarvard John A. Paulson School of Engineering and Applied Sciences, Cambridge, MA, USA.
Lauren M Baker *Harvard John A. Paulson School of Engineering and Applied Sciences, Cambridge, MA, USA.
Jaehyun Bae *Harvard John A. Paulson School of Engineering and Applied Sciences, Cambridge, MA, USA.
Franchino PorciunculaHarvard John A. Paulson School of Engineering and Applied Sciences, Cambridge, MA, USA.
Blandine F ClémentHarvard John A. Paulson School of Engineering and Applied Sciences, Cambridge, MA, USA.
Christopher SiviyHarvard John A. Paulson School of Engineering and Applied Sciences, Cambridge, MA, USA.
Richard W NuckolsHarvard John A. Paulson School of Engineering and Applied Sciences, Cambridge, MA, USA.
Teresa BakerWyss Institute for Biologically Inspired Engineering, Boston, MA, USA.
Regina SloutskyWyss Institute for Biologically Inspired Engineering, Boston, MA, USA.
Dabin K ChoeHarvard John A. Paulson School of Engineering and Applied Sciences, Cambridge, MA, USA.
Kathleen O'DonnellHarvard John A. Paulson School of Engineering and Applied Sciences, Cambridge, MA, USA.
Terry D EllisDepartment of Physical Therapy, Boston University, Boston, MA, USA.
Louis N AwadWyss Institute for Biologically Inspired Engineering, Boston, MA, USA. louawad@bu.edu.
Conor J WalshHarvard John A. Paulson School of Engineering and Applied Sciences, Cambridge, MA, USA. walsh@seas.harvard.edu.
Boston University · USHeidelberg University · DEInspire Institute · USInstitute for Biomedical Engineering · CHWalsh University · US

Funding

Institutional Career DevelopmentKL2TR001411 · NCATS · BOSTON UNIVERSITY MEDICAL CAMPUS · PI MORONE, NATALIA E. · 2015 to 2024
$5.9M
Development of a Modular Soft Exosuit Platform Suitable for Community-Based NeurorehabilitationR01HD088619 · NICHD · HARVARD UNIVERSITY · PI WALSH, CONOR · 2016 to 2021
$3.9M
NCATS NIH HHS KL2 TR001411NICHD NIH HHS R01 HD088619
6 · The paper itself

Abstract

backgroundSoft robotic exosuits can provide partial dorsiflexor and plantarflexor support in parallel with paretic muscles to improve poststroke walking capacity. Previous results indicate that baseline walking ability may impact a user's ability to leverage the exosuit assistance, while the effects on continuous walking, walking stability, and muscle slacking have not been evaluated. Here we evaluated the effects of a portable ankle exosuit during continuous comfortable overground walking in 19 individuals with chronic hemiparesis. We also compared two speed-based subgroups (threshold: 0.93 m/s) to address poststroke heterogeneity.

methodsWe refined a previously developed portable lightweight soft exosuit to support continuous overground walking. We compared five minutes of continuous walking in a laboratory with the exosuit to walking without the exosuit in terms of ground clearance, foot landing and propulsion, as well as the energy cost of transport, walking stability and plantarflexor muscle slacking.

resultsExosuit assistance was associated with improvements in the targeted gait impairments: 22% increase in ground clearance during swing, 5° increase in foot-to-floor angle at initial contact, and 22% increase in the center-of-mass propulsion during push-off. The improvements in propulsion and foot landing contributed to a 6.7% (0.04 m/s) increase in walking speed (R

conclusionsThe immediate restorative benefits of the exosuit presented here underline its promise for rehabilitative gait training in poststroke individuals.

Indexed as

RoboticsStrokeGaitHumansLower ExtremityWalkingExoskeletonGround clearancePush-offRehabilitationSoft exosuitStrokeWalking speed

Identifiers

PMID37658408
PMCPMC10474762
OpenAlexW4386385556

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.