Evidence map›Paper›PMID 37658229›Full record

ArticleScientific reports2023

Associations between doses of fall-risk-increasing drugs (FRIDs) and falls of hospitalized patients.

Yu-Kai Yang, Chew-Teng Kor, Yi-Wei Sun, Hsin-Yu Wang, Yuan-Ting Yang, Sen-Yung Liu

Abstract read
In one paragraph

Article in Scientific reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Observational
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Yu-Kai YangDepartment of Physical Medicine and Rehabilitation, Changhua Christian Hospital, 135 Nanhsiao Street, Changhua City, 50006, Taiwan, ROC.
Chew-Teng KorBig Data Center, Changhua Christian Hospital, Changhua City, Taiwan, ROC.
Yi-Wei SunDepartment of Pharmacy, Changhua Christian Hospital, Changhua City, Taiwan, ROC.
Hsin-Yu WangDepartment of Pharmacy, Changhua Christian Hospital, Changhua City, Taiwan, ROC.
Yuan-Ting YangDepartment of Pharmacy, Changhua Christian Hospital, Changhua City, Taiwan, ROC.
Sen-Yung LiuDepartment of Physical Medicine and Rehabilitation, Changhua Christian Hospital, 135 Nanhsiao Street, Changhua City, 50006, Taiwan, ROC. 88925@cch.org.tw.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Falls are a serious public health problem in the aging population because of the associated clinical and socioeconomic impact. Although previous studies have investigated fall-risk-increasing drugs (FRIDs), few studies have focused on dosage among adult inpatients. This study aimed to evaluate associations between fall risk and dosage of different FRIDs classes in hospital inpatients. Inpatients who experienced falls at medical or surgical wards of Changhua Christian Hospital from January 2017 to December 2021 were identified and matched by age, sex, and hospital ward to randomly selected controls (four per case). Anonymous patient data were extracted from the hospital medical data repository, including demographic characteristics, comorbidities, fall-risk scores, and drug prescriptions. Medication dosages were computed using the anatomical therapeutic chemical classification and the defined daily dose system of the World Health Organization. A total of 852 cases and 3408 controls were identified as eligible. Reducing the use of CNS-active medications, administering lower doses of sedative-hypnotics, prescribing sufficient dopaminergic anti-Parkinson agents, and using NSAIDs instead of opioids are imperative in preventing falls among hospitalized patients according to the findings in the study.

Indexed as

AgingInpatientsAdultAgedAnalgesics, OpioidAnti-Inflammatory Agents, Non-SteroidalHumansRisk FactorsAnalgesics, OpioidAnti-Inflammatory Agents, Non-Steroidal

Identifiers

PMID37658229
PMCPMC10474018

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.