Evidence map›Paper›PMID 37658161›Full record

ArticleCommunications biology2023

Two-sample mendelian randomization reveals a causal association between membranous nephropathy and lung cancer.

Kezhen Yang, Xiaofeng Ding, Jipeng Liu, Saisai Liu, Qingguo Liu, Jianhua Li, Pingna Zhang

Open access · goldAbstract read
In one paragraph

Article in Communications biology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.0field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 5 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 5 institutions in 1 country.

Kezhen Yang *Department of Rehabilitation Medicine, Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, 3 East Qingchun Road, Hangzhou, Zhejiang, 310016, China.ORCID http://orcid.org/0000-0003-2469-1494
Xiaofeng Ding *Shanghai Skin Disease Hospital, School of Medicine, Tongji University, Shanghai, China.
Jipeng Liu *School of Acupuncture-Moxibustion and Tuina, Beijing University of Chinese Medicine, Beijing, 102488, China.
Saisai LiuChina-Japan Friendship Hospital, Beijing, China.
Qingguo LiuChina-Japan Friendship Hospital, Beijing, China. 17888808738@163.com.ORCID http://orcid.org/0000-0002-2119-9392
Jianhua LiDepartment of Rehabilitation Medicine, Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, 3 East Qingchun Road, Hangzhou, Zhejiang, 310016, China. zjdxsyfkfk@126.com.ORCID http://orcid.org/0000-0002-9994-4057
Pingna ZhangDepartment of Nephrology, The First Affiliated Hospital of Zhejiang Chinese Medical University (Zhejiang Provincial Hospital of Chinese Medicine), Hangzhou, China. 18051987251@163.com.ORCID http://orcid.org/0000-0001-8711-9749
China-Japan Friendship Hospital · CNSir Run Run Shaw Hospital · CNBeijing University of Chinese Medicine · CNTongji University · CNZhejiang Chinese Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A risk association between membranous nephropathy (MN) and lung cancer is reported, but traditional observational studies cannot provide strong evidence of its causality. This study aimed to assess genome-wide association studies data for a causal relationship between MN and lung cancer using a two-sample Mendelian randomization (MR) approach. Inverse-variance weighted, and MR Egger regression techniques were used to determine the association of genetic variants from cohorts of MN and lung cancer patients. Independent genetic variants with genome-wide significance (P < 5×10

Indexed as

Cigarette SmokingGlomerulonephritis, MembranousLung NeoplasmsAgedGenome-Wide Association StudyHumansMendelian Randomization Analysis

Identifiers

PMID37658161
PMCPMC10474265
OpenAlexW4386378963

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.