ArticleScientific reports2023
Pathogenic Leptospira are widespread in the urban wildlife of southern California.
Article in Scientific reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
24 citing papers in PubMed, 28 citations in OpenAlex.
- A systematic review ofOne health (Amsterdam, Netherlands) · 2026Article
- Draft genome sequence ofMicrobiology resource announcements · 2026Article
- Clinical and molecular characterization of an outbreak of leptospirosis in dogs from Los Angeles County, California, USA, 2021.Journal of clinical microbiology · 2026Article
- Environmental Detection of PathogenicPathogens (Basel, Switzerland) · 2026Article
- Detection of Leptospira in cane toads (Rhinella jimi) from urban and rural Paraíba, Brazil.The Veterinary record · 2026Article
- Invasive Alien Species of European Union Concern: A Systematic Review of High-Priority Pathogens in 22 Species in a One Health Framework.Animals : an open access journal from MDPI · 2026Review
- Serological and molecular evidence of Leptospira spp. in martens from Poland.BMC veterinary research · 2026Article
- Leptospirosis in Southeast Asia: Investigating Seroprevalence, Transmission Patterns, and Diagnostic Challenges.Tropical medicine and infectious disease · 2026Review
- Genomic and ecological systems-thinking framework for pathogenicFrontiers in public health · 2026Article
- Host-Driven Genetic Diversity ofTransboundary and emerging diseases · 2026Article
- Exploring individual differences in the impact of cognitive constraints on prosocial decision-making via intrinsic brain connectivity.Brain imaging and behavior · 2025Article
- Whole Genome Characterization ofPathogens (Basel, Switzerland) · 2025Article
- DNA metabarcoding analysis revealed a silent prevalence of environmental pathogenicOne health (Amsterdam, Netherlands) · 2025Article
- European Pine Marten (Veterinary sciences · 2025Article
- Climate change will amplify the impacts of harmful microorganisms in aquatic ecosystems.Nature microbiology · 2025Review
- Predictive multi-omic biomarkers for urban zoonotic spillover detection: an integrative review.Frontiers in public health · 2025Review
- The Relationship Between the Spatial Occurrence ofPathogens (Basel, Switzerland) · 2024Article
- Characterisation of pathogenicEpidemiology and infection · 2024Article
- Leptospirosis in the Platypus (Animals : an open access journal from MDPI · 2024Article
- Navigating cross-reactivity and host species effects in a serological assay: A case study of the microscopic agglutination test for Leptospira serology.PLoS neglected tropical diseases · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
23 authors at 6 institutions in 4 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Leptospirosis, the most widespread zoonotic disease in the world, is broadly understudied in multi-host wildlife systems. Knowledge gaps regarding Leptospira circulation in wildlife, particularly in densely populated areas, contribute to frequent misdiagnoses in humans and domestic animals. We assessed Leptospira prevalence levels and risk factors in five target wildlife species across the greater Los Angeles region: striped skunks (Mephitis mephitis), raccoons (Procyon lotor), coyotes (Canis latrans), Virginia opossums (Didelphis virginiana), and fox squirrels (Sciurus niger). We sampled more than 960 individual animals, including over 700 from target species in the greater Los Angeles region, and an additional 266 sampled opportunistically from other California regions and species. In the five target species seroprevalences ranged from 5 to 60%, and infection prevalences ranged from 0.8 to 15.2% in all except fox squirrels (0%). Leptospira phylogenomics and patterns of serologic reactivity suggest that mainland terrestrial wildlife, particularly mesocarnivores, could be the source of repeated observed introductions of Leptospira into local marine and island ecosystems. Overall, we found evidence of widespread Leptospira exposure in wildlife across Los Angeles and surrounding regions. This indicates exposure risk for humans and domestic animals and highlights that this pathogen can circulate endemically in many wildlife species even in densely populated urban areas.
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