Evidence map›Paper›PMID 37657881›Full record

ReviewAdvances in kidney disease and health2023

Management of Hepatitis C Virus and Hepatitis B Virus Infection in the Setting of Kidney Disease.

Purva Sharma, Rani Sawtell, Qiyu Wang, Meghan E Sise

Open access · greenAbstract readReview
In one paragraph

Review in Advances in kidney disease and health, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
1.8field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it, 9 citations in OpenAlex.

  1. Guideline
  2. Article
  3. Review
  4. Current perspectives of viral hepatitis.World journal of gastroenterology · 2024
    Review
  5. Post-Transplant Glomerulonephritis: Challenges and Solutions.International journal of nephrology and renovascular disease · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Purva SharmaDepartment of Medicine, Division of Nephrology, Donald and Barbara Zucker School of Medicine at Hofstra/Northwell; Glomerular Disease Center at Northwell Health, Hempstead, NY.
Rani SawtellDepartment of Medicine, Division of Nephrology, Massachusetts General Hospital, Boston, MA.
Qiyu WangDepartment of Medicine, Division of Nephrology, Massachusetts General Hospital, Boston, MA.
Meghan E SiseDepartment of Medicine, Division of Nephrology, Massachusetts General Hospital, Boston, MA. Electronic address: msise@partners.org.
Massachusetts General Hospital · USNorthwell Health · US

Funding

Effect of Hepatitis C Virus Eradication on Chronic Kidney Disease ProgressionK23DK117014 · NIDDK · MASSACHUSETTS GENERAL HOSPITAL · PI SISE, MEGHAN E. · 2018 to 2022
$865k
NIDDK NIH HHS K23 DK117014
6 · The paper itself

Abstract

Treatment of chronic hepatitis C virus (HCV) and hepatitis B virus (HBV) infection poses unique challenges in patients with kidney disease. Direct-acting antivirals have been a major breakthrough in eradicating HCV infection, and several pangenotypic regimens are available for patients with chronic kidney disease or end-stage kidney disease requiring dialysis with high cure rates and no need for dose adjustment. Direct-acting antiviral therapy alone can treat HCV-associated cryoglobulinemic glomerulonephritis; concurrent antiviral and immunosuppressive therapy is needed for cases of severe, organ-threatening manifestations of cryoglobulinemia. Immunosuppression may be needed for HBV-associated kidney disease (polyarteritis nodosa or membranous nephropathy) when there is evidence of severe immune-mediated injury while weighing the risk of potential viral activation. Most HBV antiviral agents need to be dose-adjusted in patients with chronic kidney disease or end-stage kidney disease requiring dialysis, and drug-drug interactions need to be carefully evaluated in patients with kidney transplants. Considerations for accepting HCV- and HBV-infected donors for kidney transplantation are discussed.

Indexed as

Hepatitis BHepatitis CHepatitis C, ChronicKidney Failure, ChronicRenal Insufficiency, ChronicAntiviral AgentsHepacivirusHepatitis B virusHumansAntiviral Agentscryoglobulinemiahepatitis B virusHepatitis C virusliver diseasemembranous

Identifiers

PMID37657881
PMCPMC10479952
OpenAlexW4386296374

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.