Evidence map›Paper›PMID 37656492›Full record

ArticleJMIR public health and surveillance2023

Trends in Opioid Medication Adherence During the COVID-19 Pandemic: Retrospective Cohort Study.

Amir Marashi, David Warren, Gary Call, Mark Dras

Open access · goldAbstract read
In one paragraph

Article in JMIR public health and surveillance, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 80% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Amir MarashiSchool of Computing, Macquarie University, Macquarie Park, Australia.ORCID 0000-0003-2783-223X
David WarrenSchool of Computing, Macquarie University, Macquarie Park, Australia.ORCID 0000-0002-4914-1344
Gary CallGainwell Technologies, Tysons, VA, United States.ORCID 0009-0003-6179-8351
Mark DrasSchool of Computing, Macquarie University, Macquarie Park, Australia.ORCID 0000-0001-9908-7182
Macquarie University · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe recent pandemic had the potential to worsen the opioid crisis through multiple effects on patients' lives, such as the disruption of care. In particular, good levels of adherence with respect to medication for opioid use disorder (MOUD), recognized as being important for positive outcomes, may be disrupted.

objectiveThis study aimed to investigate whether patients on MOUD experienced a drop in medication adherence during the recent COVID-19 pandemic.

methodsThis retrospective cohort study used Medicaid claims data from 6 US states from 2018 until the start of 2021. We compared medication adherence for people on MOUD before and after the beginning of the COVID-19 pandemic in March 2020. Our main measure was the proportion of days covered (PDC), a score that measures patients' adherence to their MOUD. We carried out a breakpoint analysis on PDC, followed by a patient-level beta regression analysis with PDC as the dependent variable while controlling for a set of covariates.

resultsA total of 79,991 PDC scores were calculated for 37,604 patients (age: mean 37.6, SD 9.8 years; sex: n=17,825, 47.4% female) between 2018 and 2021. The coefficient for the effect of COVID-19 on PDC score was -0.076 and was statistically significant (odds ratio 0.925, 95% CI 0.90-0.94).

conclusionsThe COVID-19 pandemic was negatively associated with patients' adherence to their medication, which had declined since the beginning of the pandemic.

Indexed as

COVID-19Opioid-Related DisordersAdultAnalgesics, OpioidFemaleHumansMaleMedication AdherencePandemicsRetrospective StudiesUnited StatesAnalgesics, Opioidbeta regression analysisbreakpoint analysiscareCOVID-19medicationmedication for opioid use disorderMOUDopioidopioid crisisopioidsopioid use disorderpandemicpatientpublic healthtreatment

Identifiers

PMID37656492
PMCPMC10504620
OpenAlexW4386346951

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.