Evidence map›Paper›PMID 37656290›Full record

ArticleChild psychiatry and human development2025

Novel Insights into Somatic Comorbidities in Children and Adolescents Across Psychiatric Diagnoses: An Explorative Study.

Jet B Muskens, Wietske A Ester, Helen Klip, Janneke Zinkstok, Martine van Dongen-Boomsma, Wouter G Staal

Open access · hybridAbstract read
In one paragraph

Article in Child psychiatry and human development, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.1field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 5 institutions in 1 country.

Jet B MuskensKarakter Child and Adolescent Psychiatry University Centre Nijmegen, Nijmegen, The Netherlands. j.muskens@karakter.com.
Wietske A EsterSarr Autism Rotterdam, Youz Child and Adolescence Psychiatry, Dynamostraat 18, Rotterdam, 3083 AK, The Netherlands.
Helen KlipKarakter Child and Adolescent Psychiatry University Centre Nijmegen, Nijmegen, The Netherlands.
Janneke ZinkstokKarakter Child and Adolescent Psychiatry University Centre Nijmegen, Nijmegen, The Netherlands.
Martine van Dongen-BoomsmaKarakter Child and Adolescent Psychiatry University Centre Nijmegen, Nijmegen, The Netherlands.
Wouter G StaalKarakter Child and Adolescent Psychiatry University Centre Nijmegen, Nijmegen, The Netherlands.
Radboud University Nijmegen · NLCodarts Rotterdam · NLDutch Expert Centre for Screening · NLKarakter · NLUniversity Medical Center Utrecht · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Many children with psychiatric disorders display somatic symptoms, although these are frequently overlooked. As somatic morbidity early in life negatively influences long-term outcomes, it is relevant to assess comorbidity. However, studies of simultaneous psychiatric and somatic assessment in children are lacking. The aim of this study was to assess the prevalence of somatic comorbidities in a clinical sample of children and adolescents with psychiatric disorders in a naturalistic design. Data were assessed from 276 children with various psychiatric disorders (neurodevelopmental disorders, affective disorders, eating disorders and psychosis) aged 6-18 years. These data were collected as part of routine clinical assessment, including physical examination and retrospectively analyzed. For a subsample (n = 97), blood testing on vitamin D3, lipid spectrum, glucose and prolactin was available. Results of this cross-sectional study revealed that food intake problems (43%) and insomnia (66%) were common. On physical examination, 20% of the children were overweight, 12% displayed obesity and 38% had minor physical anomalies. Blood testing (n = 97) highlighted vitamin D3 deficiency (< 50 nmol/L) in 73% of the children. None of the predefined variables (gender, age, medication and socioeconomic factors) contributed significantly to the prevalence of somatic comorbidities. The main somatic comorbidities in this broad child- and adolescent psychiatric population consisted of (1) problems associated with food intake, including obesity and vitamin D3 deficiency and (2) sleeping problems, mainly insomnia. Child and adolescent psychiatrists need to be aware of potential somatic comorbidities and may promote a healthy lifestyle.

Indexed as

Feeding and Eating DisordersMental DisordersNeurodevelopmental DisordersSleep Initiation and Maintenance DisordersAdolescentChildComorbidityCross-Sectional StudiesFemaleHumansMaleMood DisordersPrevalencePsychotic DisordersRetrospective StudiesVitamin D DeficiencyChild and adolescent psychiatryInsomniaObesityPhysical healthSomatic comorbidityVitamin D deficiency

Identifiers

PMID37656290
PMCPMC12095410
OpenAlexW4386346760

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.