Evidence map›Paper›PMID 37656281›Full record

ArticleEuropean journal of applied physiology2024

Type IIx muscle fibers are related to poor body composition, glycemic and lipidemic blood profiles in young females: the protective role of type I and IIa muscle fibers.

Spyridon Methenitis, T Nomikos, T Mpampoulis, E Kontou, E Evangelidou, C Papadopoulos, G Papadimas, G Terzis

Abstract read
PubMed Publisher
In one paragraph

Article in European journal of applied physiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
0.6field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it, 3 citations in OpenAlex.

  1. Knee Extensor Structure and Function in Children, Adolescents, Adults, and Older Adults With Obesity: A Systematic Review and Meta-Analysis.Obesity reviews : an official journal of the International Association for the Study of Obesity · 2025
    Pooled it
  2. Article
  3. Fat-Free Mass: Friend or Foe to Metabolic Health?Journal of cachexia, sarcopenia and muscle · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Spyridon MethenitisSports Performance Laboratory, School of Physical Education and Sports Science, National and Kapodistrian University of Athens, 172 37, Ethnikis Antistassis 41, Daphne, Athens, Greece. smetheni@phed.uoa.gr.ORCID http://orcid.org/0000-0003-4370-1395
T NomikosDepartment of Nutrition & Dietetics, School of Health Sciences and Education, Harokopio University, 17671, Athens, Greece.ORCID http://orcid.org/0000-0003-0536-6397
T MpampoulisSports Performance Laboratory, School of Physical Education and Sports Science, National and Kapodistrian University of Athens, 172 37, Ethnikis Antistassis 41, Daphne, Athens, Greece.ORCID http://orcid.org/0000-0002-2972-8527
E KontouSports Performance Laboratory, School of Physical Education and Sports Science, National and Kapodistrian University of Athens, 172 37, Ethnikis Antistassis 41, Daphne, Athens, Greece.
E EvangelidouDepartment of Infection Control, G.N.N. Ionias "Konstantopouleio-Patision" hospital, 142 33, N. Ionia, Greece.ORCID http://orcid.org/0000-0002-7570-2176
C PapadopoulosA' Neurology Clinic, Aiginition Hospital, Medical School, National and Kapodistrian University of Athens, 15784, Zografou, Greece.
G PapadimasA' Neurology Clinic, Aiginition Hospital, Medical School, National and Kapodistrian University of Athens, 15784, Zografou, Greece.ORCID http://orcid.org/0000-0003-0163-4091
G TerzisSports Performance Laboratory, School of Physical Education and Sports Science, National and Kapodistrian University of Athens, 172 37, Ethnikis Antistassis 41, Daphne, Athens, Greece.ORCID http://orcid.org/0000-0002-0049-5395
National and Kapodistrian University of Athens · GRAgia Olga Hospital · GRHarokopio University of Athens · GR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThe aim of the present study was to investigate the association between muscle fiber composition, body composition, resting glycemic-lipidemic blood profiles, in apparently healthy, young, active females.

methodsThirty-four young healthy female volunteers were allocated into two groups, depending on their Vastus Lateralis type IIx muscle fibers percent cross-sectional area (%CSA; H: high type IIx %CSA; L: low type IIx %CSA). Body composition was determined via dual-energy X-ray absorptiometry. Venous blood samples were collected for the determination of resting serum glucose, Insulin, Apo-A1, HOMA-IR, triglycerides (TG), total cholesterol (TC), High-density lipoprotein (HDL-C), and Low-density lipoprotein (LDL-C) concentrations. Nutritional intake was also evaluated.

resultsIndividuals of the H group have significantly higher body mass, body fat percentage-mass, and resting blood indices of glycemic and lipidemic profiles, compared to those of L group (p < 0.001). Increased type IIx and low type I, IIa muscle fibers %CSAs were linked with poorer body composition, glycemic and lipidemic blood profiles (r: - 0.722 to 0.740, p < 0.001). Linear regression analyses revealed that the impact of muscle fibers %CSA (B coefficients ranged between - 0.700 and 0.835) on the above parameters, was at least, of the same or even of greater magnitude as that of body composition and daily nutritional intake (B: - 0.700 to 0.666).

conclusionIncreased type IIx and low Type I, IIa %CSAs are associated with poorer body composition and glycemic-lipidemic profiles in young healthy females. The contribution of the muscle fiber %CSA on health status seems to be comparable to that of nutrition and body composition.

Indexed as

Body CompositionMuscle Fibers, SkeletalFemaleHumansInsulinNutritional StatusQuadriceps MuscleInsulinHigh-density lipoproteinHOMA-IRInsulinLow-density lipoproteinMuscle fiber compositionNutrition

Identifiers

PMID37656281
OpenAlexW4386346601

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.