Evidence map›Paper›PMID 37655912›Full record

ArticleJournal of bacteriology2023

Butyrate enhances

Michelle A Baldassare, Disha Bhattacharjee, Julian D Coles, Sydney Nelson, C Alexis McCollum, Anna M Seekatz

Open access · hybridAbstract read
In one paragraph

Article in Journal of bacteriology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
3.5field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 19 citations in OpenAlex.

  1. Review
  2. [Butyrate alleviatesNan fang yi ke da xue xue bao = Journal of Southern Medical University · 2026
    Article
  3. EndD mediates butyrate-dependent toxin release inbioRxiv : the preprint server for biology · 2026
    Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. The emerging view on the roles of butyrate inInfection and immunity · 2025
    Review
  9. Unravelling three-way interactions betweenJournal of medical microbiology · 2025
    Review
  10. Review
  11. Review
  12. Review
  13. Review
  14. Review
  15. Uncovering newMicrobiology spectrum · 2024
    Article
  16. Review
  17. Article
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Michelle A Baldassare *Department of Biological Sciences, Clemson University , Clemson, South Carolina, USA.
Disha Bhattacharjee *Department of Biological Sciences, Clemson University , Clemson, South Carolina, USA.ORCID 0000-0002-2186-5084
Julian D ColesDepartment of Biological Sciences, Clemson University , Clemson, South Carolina, USA.
Sydney NelsonDepartment of Biological Sciences, Clemson University , Clemson, South Carolina, USA.
C Alexis McCollumDepartment of Biological Sciences, Clemson University , Clemson, South Carolina, USA.
Anna M SeekatzDepartment of Biological Sciences, Clemson University , Clemson, South Carolina, USA.ORCID 0000-0003-2586-7498
Clemson University · US

Funding

The role of acetate fermentation in Entamoeba histolytica growth and infectionP20GM109094 · NIGMS · CLEMSON UNIVERSITY · PI KOZUBOWSKI, LUKASZ · 2016 to 2020
$10.4M
Niche Partitioning of Commensal Clostridia in the GutR35GM150609 · NIGMS · CLEMSON UNIVERSITY · PI Anna Maria Seekatz · 2023 to 2026
$1.5M
Critical functions of the gut microbiota that mediate recovery from recurrent Clostridium difficile infectionK01DK111794 · NIDDK · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI SEEKATZ, ANNA MARIA · 2018 to 2022
$706k
NIDDK NIH HHS K01 DK111794NIGMS NIH HHS P20 GM109094
6 · The paper itself

Abstract

Short-chain fatty acids (SCFAs) are products of bacterial fermentation that help maintain important gut functions such as maintenance of the intestinal barrier, cell signaling, and immune homeostasis. The main SCFAs acetate, propionate, and butyrate have demonstrated beneficial effects for the host, including its importance in alleviating infections caused by pathogens such as

Indexed as

Clostridioides difficileClostridium InfectionsAnimalsBacterial ProteinsButyratesClostridioidesFermentationHumansBacterial ProteinsButyratesbutyrateClostridioides difficilegrowth assaymetabolismsporulation

Identifiers

PMID37655912
PMCPMC10521354
OpenAlexW4386346962

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.