Evidence map›Paper›PMID 37655908›Full record

ArticleMicrobiology spectrum2023

Impact of storage time in dried blood samples (DBS) and dried plasma samples (DPS) for point-of-care hepatitis C virus (HCV) RNA quantification and HCV core antigen detection.

Paloma Troyano-Hernáez, Pedro Herrador, Francisco Gea, Beatriz Romero-Hernández, Gabriel Reina, Agustín Albillos, Juan Carlos Galán, África Holguín

Open access · goldAbstract read
In one paragraph

Article in Microbiology spectrum, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.2field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Paloma Troyano-HernáezMicrobiology Department, HIV-1 Molecular Epidemiology Laboratory, Ramón y Cajal University Hospital-Ramón y Cajal Institute for Health Research (IRYCIS) and RITIP-CoRISpe , Madrid, Spain.ORCID 0000-0002-0684-4605
Pedro HerradorMicrobiology Department, HIV-1 Molecular Epidemiology Laboratory, Ramón y Cajal University Hospital-Ramón y Cajal Institute for Health Research (IRYCIS) and RITIP-CoRISpe , Madrid, Spain.
Francisco GeaGastroenterology Department, Ramón y Cajal University Hospital-Ramón y Cajal Institute for Health Research (IRYCIS) , Madrid, Spain.
Beatriz Romero-HernándezMicrobiology Department, Ramón y Cajal University Hospital-Ramón y Cajal Institute for Health Research (IRYCIS) , Madrid, Spain.
Gabriel ReinaMicrobiology Department, Clínica Universidad de Navarra , Pamplona, Spain.
Agustín AlbillosGastroenterology Department, Ramón y Cajal University Hospital-Ramón y Cajal Institute for Health Research (IRYCIS) , Madrid, Spain.
Juan Carlos GalánMicrobiology Department, Ramón y Cajal University Hospital-Ramón y Cajal Institute for Health Research (IRYCIS) , Madrid, Spain.
África HolguínMicrobiology Department, HIV-1 Molecular Epidemiology Laboratory, Ramón y Cajal University Hospital-Ramón y Cajal Institute for Health Research (IRYCIS) and RITIP-CoRISpe , Madrid, Spain.
Instituto Cajal · ESNavarre Institute of Health Research · ESUniversidad de Alcalá · ES

Funding

AbbVie Inc. | AbbVie Deutschland (AbbVie Germany)MEC | Instituto de Salud Carlos III (ISCIII) CM19/00057
6 · The paper itself

Abstract

importanceHepatitis C infection remains a global burden despite the effectiveness of antivirals. In the WHO roadmap to accomplish HCV elimination by 2030, HCV diagnosis is one of the main targets. However, identifying patients in resource-limited settings and high-risk populations with limited access to healthcare remains a challenge and requires innovative approaches that allow decentralized testing. The significance of our research is in verifying the good performance of dried samples for HCV diagnosis using two different diagnostics assays and considering the effect of room temperature storage in this sample format. We confirmed dried samples are an interesting alternative for HCV screening and reflex testing in resource-limited settings or high-risk populations.

Indexed as

core antigenDBSDPSdried bloodHCVhepatitis CPOCviral load

Identifiers

PMID37655908
PMCPMC10581200
OpenAlexW4386347610

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.