Evidence map›Paper›PMID 37655618›Full record

ArticleHeadache2023

Resting-state electroencephalography microstate dynamics altered in patients with migraine with and without aura-A pilot study.

Xiangyu Lei, Meng Wei, Liang Wang, Chenyu Liu, Qin Liu, Xiaoyu Wu, Qingfan Wang, Xinyue Sun, Guogang Luo, Yi Qi

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In one paragraph

Article in Headache, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
2.0field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it, 9 citations in OpenAlex.

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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Xiangyu LeiDepartment of Neurology, the First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China.
Meng WeiDepartment of Neurology, the First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China.
Liang WangDepartment of Neurology, the First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China.
Chenyu LiuDepartment of Neurology, the First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China.
Qin LiuDepartment of Neurology, the First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China.
Xiaoyu WuDepartment of Neurology, the First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China.
Qingfan WangDepartment of Neurology, the First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China.
Xinyue SunDepartment of Neurology, the First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China.
Guogang LuoDepartment of Neurology, the First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China.
Yi QiDepartment of Neurology, the First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China.
First Affiliated Hospital of Xi'an Jiaotong University · CN

Funding

Natural Science Foundation of Shaanxi Province 2022JQ-987Research and Development Funds of Xian Jiaotong University First Affiliated Hospital 2021ZYTS-12the First Affiliated Hospital of Xi'an Jiaotong University Foundation 2019QN-13
6 · The paper itself

Abstract

objectiveTo evaluate electroencephalography (EEG) microstate differences between patients with migraine with aura (MWA), patients with migraine without aura (MWoA), and healthy controls (HC).

backgroundPrevious research employing microstate analysis found unique microstate alterations in patients with MWoA; however, it is uncertain how microstates appear in patients with MWA.

methodsThis study was conducted at the Headache Clinic of the First Affiliated Hospital of Xi'an Jiaotong University. In total, 30 patients with MWA, 30 with MWoA, and 30 HC were enrolled in this cross-sectional study. An EEG was recorded for all participants under resting state. The microstate parameters of four widely recognized microstate classes A-D were calculated and compared across the three groups.

resultsThe occurrence of microstate B (MsB) in the MWoA group was significantly higher than in the HC (p = 0.006, Cohen's d = 0.72) and MWA (p = 0.016, Cohen's d = 0.57) groups, while the contribution of MsB was significantly increased in the MWoA group compared to the HC group (p = 0.016, Cohen's d = 0.64). Microstate A (MsA) displayed a longer duration in the MWA group compared to the MWoA group (p = 0.007, Cohen's d = 0.69). Furthermore, the transition probability between MsB and microstate D was significantly increased in the MWoA group compared to the HC group (p = 0.009, Cohen's d = 0.68 for B to D; p = 0.007, Cohen's d = 0.71 for D to B). Finally, the occurrence and contribution of MsB were positively related to headache characteristics in the MWoA group but negatively in the MWA group, whereas the duration of MsA was positively related to the visual analog scale in the MWA group (all p < 0.05).

conclusionsPatients with MWA and MWoA have altered microstate dynamics, indicating that resting-state brain network disorders may play a role in migraine pathogenesis. Microstate parameters may have the potential to aid clinical management, which needs to be investigated further.

Indexed as

Brain DiseasesEpilepsyMigraine with AuraMigraine without AuraCross-Sectional StudiesElectroencephalographyHeadacheHumansPilot Projectselectroencephalographymicrostate dynamicsmigraine

Identifiers

PMID37655618
OpenAlexW4386346828

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.