Evidence map›Paper›PMID 37655498›Full record

ArticleCirculation. Cardiovascular imaging2023

Feasibility of Simultaneous Quantification of Myocardial and Renal Perfusion With Cardiac Positron Emission Tomography.

Jenifer M Brown, Mi-Ae Park, Marie Foley Kijewski, Brittany N Weber, Yihe Yang, Laurel Martell, Anna Perillo, Leanne Barrett, Sean Parks, Jon Hainer and 3 more

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Circulation. Cardiovascular imaging, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.4field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Article
  3. Total-body positron emission tomography: Investigating mechanisms in cardiovascular-kidney-metabolic syndrome.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2025
    Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 2 institutions in 1 country.

Jenifer M BrownHeart and Vascular Center, Division of Cardiovascular Medicine, Department of Medicine (J.M.B., B.N.W., S.D., R.B., M.F.D.C.), Brigham and Women's Hospital, Harvard Medical School, Boston, MA.ORCID 0000-0002-6647-639X
Mi-Ae ParkDepartment of Radiology, UT Southwestern Medical Center, Dallas, TX (M.-A.P.).ORCID 0000-0003-0806-129X
Marie Foley KijewskiCardiovascular Imaging Program, Departments of Medicine and Radiology (J.M.B., M.F.K., B.N.W., L.M., A.P., L.B., S.P., J.H., S.D., R.B., M.F.D.C.), Brigham and Women's Hospital, Harvard Medical School, Boston, MA.
Brittany N WeberHeart and Vascular Center, Division of Cardiovascular Medicine, Department of Medicine (J.M.B., B.N.W., S.D., R.B., M.F.D.C.), Brigham and Women's Hospital, Harvard Medical School, Boston, MA.ORCID 0000-0002-0177-2091
Yihe YangDepartment of Pathology (Y.Y.), Brigham and Women's Hospital, Harvard Medical School, Boston, MA.
Laurel MartellCardiovascular Imaging Program, Departments of Medicine and Radiology (J.M.B., M.F.K., B.N.W., L.M., A.P., L.B., S.P., J.H., S.D., R.B., M.F.D.C.), Brigham and Women's Hospital, Harvard Medical School, Boston, MA.
Anna PerilloCardiovascular Imaging Program, Departments of Medicine and Radiology (J.M.B., M.F.K., B.N.W., L.M., A.P., L.B., S.P., J.H., S.D., R.B., M.F.D.C.), Brigham and Women's Hospital, Harvard Medical School, Boston, MA.
Leanne BarrettCardiovascular Imaging Program, Departments of Medicine and Radiology (J.M.B., M.F.K., B.N.W., L.M., A.P., L.B., S.P., J.H., S.D., R.B., M.F.D.C.), Brigham and Women's Hospital, Harvard Medical School, Boston, MA.ORCID 0000-0003-0667-8720
Sean ParksCardiovascular Imaging Program, Departments of Medicine and Radiology (J.M.B., M.F.K., B.N.W., L.M., A.P., L.B., S.P., J.H., S.D., R.B., M.F.D.C.), Brigham and Women's Hospital, Harvard Medical School, Boston, MA.ORCID 0000-0001-7893-8136
Jon HainerCardiovascular Imaging Program, Departments of Medicine and Radiology (J.M.B., M.F.K., B.N.W., L.M., A.P., L.B., S.P., J.H., S.D., R.B., M.F.D.C.), Brigham and Women's Hospital, Harvard Medical School, Boston, MA.ORCID 0000-0002-0572-912X
Sharmila DorbalaHeart and Vascular Center, Division of Cardiovascular Medicine, Department of Medicine (J.M.B., B.N.W., S.D., R.B., M.F.D.C.), Brigham and Women's Hospital, Harvard Medical School, Boston, MA.ORCID 0000-0003-1462-1185
Ron BlanksteinHeart and Vascular Center, Division of Cardiovascular Medicine, Department of Medicine (J.M.B., B.N.W., S.D., R.B., M.F.D.C.), Brigham and Women's Hospital, Harvard Medical School, Boston, MA.ORCID 0000-0002-8393-6562
Marcelo F Di CarliHeart and Vascular Center, Division of Cardiovascular Medicine, Department of Medicine (J.M.B., B.N.W., S.D., R.B., M.F.D.C.), Brigham and Women's Hospital, Harvard Medical School, Boston, MA.ORCID 0000-0003-3119-025X
Brigham and Women's Hospital · USSouthwestern Medical Center · US

Funding

The Harvard Clinical and Translational Science CenterUL1TR002541 · NCATS · HARVARD MEDICAL SCHOOL · PI NADLER, LEE MARSHALL · 2018 to 2022
$93.0M
Noninvasive Cardiovascular Imaging Research Training ProgramT32HL094301 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI Marcelo F DI CARLI · 2010 to 2026
$7.8M
Cardiac Perfusion, Structure, and Function across the Primary Aldosteronism SpectrumK23HL159279 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI Jenifer Michelle Brown · 2022 to 2026
$1.0M
Advanced CV imaging and immunophenotyping to study coronary vascular health in psoriasisK23HL159276 · NHLBI · UT SOUTHWESTERN MEDICAL CENTER · PI WEBER, BRITTANY NICOLE · 2021 to 2025
$962k
Mentoring Patient Oriented Research in Innovative Imaging and High-dimensional Data Approaches to Improve Outcomes in Cardiac AmyloidosisK24HL157648 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI DORBALA, SHARMILA · 2021 to 2025
$612k
NCATS NIH HHS UL1 TR002541NHLBI NIH HHS K23 HL159276NHLBI NIH HHS K23 HL159279NHLBI NIH HHS K24 HL157648NHLBI NIH HHS T32 HL094301
6 · The paper itself

Abstract

backgroundGiven the central importance of cardiorenal interactions, mechanistic tools for evaluating cardiorenal physiology are needed. In the heart and kidneys, shared pathways of neurohormonal activation, hypertension, and vascular and interstitial fibrosis implicate the relevance of systemic vascular health. The availability of a long axial field of view positron emission tomography (PET)/computed tomography (CT) system enables simultaneous evaluation of cardiac and renal blood flow.

methodsThis study evaluated the feasibility of quantification of renal blood flow using data acquired during routine, clinically indicated

resultsAmong 386 consecutive patients with myocardial perfusion PET/CT, 296 (76.7%) had evaluable images to quantify renal perfusion. PET quantification of renal blood flow was highly reproducible (intraclass correlation coefficient 0.98 [95% CI, 0.93-0.99]) and was correlated with the estimated glomerular filtration rate (

conclusionsRenal blood flow can be reliably measured from cardiac

Indexed as

AmmoniaPositron Emission Tomography Computed TomographyFeasibility StudiesFibrosisHumansKidneyPerfusionPositron-Emission TomographyReproducibility of ResultsAmmoniaperfusion imagingpositron emission tomographyrenal blood flow

Identifiers

PMID37655498
PMCPMC10529360
OpenAlexW4386346482

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.