Evidence map›Paper›PMID 37655179›Full record

ArticleLetters in biomathematics2023

GillesPy2: A Biochemical Modeling Framework for Simulation Driven Biological Discovery.

Sean Matthew, Fin Carter, Joshua Cooper, Matthew Dippel, Ethan Green, Samuel Hodges, Mason Kidwell, Dalton Nickerson, Bryan Rumsey, Jesse Reeve and 3 more

Abstract read
In one paragraph

Article in Letters in biomathematics, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Sean MatthewNational Environmental Modeling and Analysis Center (NEMAC), University of North Carolina, Asheville, NC 28804.
Fin CarterDepartment of Computer Science, University of North Carolina, Asheville, NC 28804.
Joshua CooperDepartment of Computer Science, University of North Carolina, Asheville, NC 28804.
Matthew DippelDepartment of Computer Science, University of North Carolina, Asheville, NC 28804.
Ethan GreenDepartment of Computer Science, University of North Carolina, Asheville, NC 28804.
Samuel HodgesDepartment of Computer Science, North Carolina State University, NC 27695.
Mason KidwellDepartment of Computer Science, University of North Carolina, Asheville, NC 28804.
Dalton NickersonDepartment of Computer Science, University of North Carolina, Asheville, NC 28804.
Bryan RumseyNational Environmental Modeling and Analysis Center (NEMAC), University of North Carolina, Asheville, NC 28804.
Jesse ReeveDepartment of Computer Science, University of North Carolina, Asheville, NC 28804.
Linda R PetzoldDepartment of Computer Science and Department of Mechanical Engineering, University of California, Santa Barbara, CA 93106.
Kevin R SanftDepartment of Computer Science, University of North Carolina, Asheville, NC 28804.
Brian DrawertNational Environmental Modeling and Analysis Center (NEMAC), University of North Carolina, Asheville, NC 28804.

Funding

StochSS: A Next-Generation Toolkit for Simulation-Driven Biological DiscoveryR01EB014877 · NIBIB · UNIVERSITY OF CALIFORNIA SANTA BARBARA · PI PETZOLD, LINDA R. · 2012 to 2022
$3.9M
NIBIB NIH HHS R01 EB014877
6 · The paper itself

Abstract

Stochastic modeling has become an essential tool for studying biochemical reaction networks. There is a growing need for user-friendly and feature-complete software for model design and simulation. To address this need, we present GillesPy2, an open-source framework for building and simulating mathematical and biochemical models. GillesPy2, a major upgrade from the original GillesPy package, is now a stand-alone Python 3 package. GillesPy2 offers an intuitive interface for robust and reproducible model creation, facilitating rapid and iterative development. In addition to expediting the model creation process, GillesPy2 offers efficient algorithms to simulate stochastic, deterministic, and hybrid stochastic-deterministic models.

Indexed as

HybridModelingSimulationStochastic

Identifiers

PMID37655179
PMCPMC10470263

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.