Evidence map›Paper›PMID 37654734›Full record

ArticleWilliam and Mary law review2020

GENETIC DUTIES.

Jessica L Roberts, Alexandra L Foulkes

Abstract read
In one paragraph

Article in William and Mary law review, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
  2. Practical considerations for reinterpretation of individual genetic variants.Genetics in medicine : official journal of the American College of Medical Genetics · 2023
    Article
  3. Article
  4. Article
  5. Challenges of variant reinterpretation: Opinions of stakeholders and need for guidelines.Genetics in medicine : official journal of the American College of Medical Genetics · 2022
    Article
  6. Article
  7. UNLIMITED MEDICAL LIABILITY?Emory law journal online · 2022
    Article
  8. Of Screening, Stratification, and Scores.Journal of personalized medicine · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Jessica L RobertsUniversity of Houston Law Center.
Alexandra L FoulkesUnited States District Court for the Western District of Oklahoma.

Funding

Development of recommendations and policies for genetic variant reclassificationR01HG010365 · NHGRI · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI APPELBAUM, PAUL STUART, CHUNG, WENDY K · 2018 to 2021
$2.9M
NHGRI NIH HHS R01 HG010365
6 · The paper itself

Abstract

Most of our genetic information does not change, yet the results of our genetic tests might. Labs reclassify genetic variants in response to advances in genetic science. As a result, a person who took a test in 2010 could take the same test with the same lab in 2020 and get a different result. However, no legal duty requires labs or physicians to inform patients when a lab reclassifies a variant, even if the reclassification communicates clinically actionable information. This Article considers the need for such duties and their potential challenges. In so doing, it offers much-needed guidance to physicians and labs, who may face liability, and to courts, which will hear these cases.

Identifiers

PMID37654734
PMCPMC10471136

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.