Evidence map›Paper›PMID 37654202›Full record

ArticleMolecular medicine reports2023

Celastrol attenuates human parvovirus B19 NS1‑induced NLRP3 inflammasome activation in macrophages.

Chang-Lun Huang, Der-Yuan Chen, Chih-Chen Tzang, Jhen-Wei Lin, Bor-Show Tzang, Tsai-Ching Hsu

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Molecular medicine reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.2field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 6 citations in OpenAlex.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Chang-Lun HuangDivision of Thoracic Surgery, Department of Surgery, Changhua Christian Medical Foundation Changhua Christian Hospital, Changhua 500, Taiwan, R.O.C.
Der-Yuan ChenInstitute of Medicine, Chung Shan Medical University, Taichung 402, Taiwan, R.O.C.
Chih-Chen TzangSchool of Medicine, College of Medicine, National Taiwan University, Taipei 100, Taiwan, R.O.C.
Jhen-Wei LinInstitute of Medicine, Chung Shan Medical University, Taichung 402, Taiwan, R.O.C.
Bor-Show TzangInstitute of Medicine, Chung Shan Medical University, Taichung 402, Taiwan, R.O.C.
Tsai-Ching HsuInstitute of Medicine, Chung Shan Medical University, Taichung 402, Taiwan, R.O.C.
Chung Shan Medical University · TWChanghua Christian Hospital · TWNational Taiwan University · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Human parvovirus B19 (B19V) has been strongly associated with a variety of inflammatory disorders, such as rheumatoid arthritis (RA), inflammatory bowel disease and systemic lupus erythematosus. Non‑structural protein 1 (NS1) of B19V has been demonstrated to play essential roles in the pathological processes of B19V infection due to its regulatory properties on inflammatory cytokines. Celastrol, a quinone methide isolated from

Indexed as

Arthritis, RheumatoidParvovirus B19, HumanCytokinesHumansInflammasomesMacrophagesNLR Family, Pyrin Domain-Containing 3 ProteinPentacyclic TriterpenescelastrolCytokinesInflammasomesNLR Family, Pyrin Domain-Containing 3 ProteinPentacyclic Triterpenescelastrolhuman parvovirus B19inflammasomeinflammationmacrophagesnon‑structural protein 1

Identifiers

PMID37654202
PMCPMC10502933
OpenAlexW4386326602

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.