Evidence map›Paper›PMID 37653670›Full record

ArticleJournal of experimental zoology. Part A, Ecological and integrative physiology2023

Impact of volume and rate of milk delivery on coordination of respiration and swallowing in infant pigs.

Francois D H Gould, Christopher J Mayerl, Khaled Adjerid, Chloe Edmonds, Nicole Charles, Maxwell Johnson, Rebecca Z German

Open access · bronzeAbstract read
In one paragraph

Article in Journal of experimental zoology. Part A, Ecological and integrative physiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.7field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
  3. Longitudinal Changes in Aerodigestive Responses to Varying Nipple Properties in Infant Pigs.Journal of experimental zoology. Part A, Ecological and integrative physiology · 2025
    Article
  4. Videofluoroscopy of the aerodigestive tract inFrontiers in veterinary science · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 1 country.

Francois D H GouldCell Biology and Neuroscience, Rowan School of Osteopathic Medicine, Stratford, New Jersey, USA.ORCID 0000-0003-3229-2602
Christopher J MayerlBiological Sciences, Northern Arizona University, Flagstaff, Arizona, USA.ORCID 0000-0003-0402-8388
Khaled AdjeridBiomedical Engineering, Tulane University, New Orleans, Los Angeles, USA.ORCID 0000-0002-9076-616X
Chloe EdmondsAnatomy and Neuroscience, Northeast Ohio Medical University, Rootstown, Ohio, USA.ORCID 0000-0001-6150-2221
Nicole CharlesCell Biology and Neuroscience, Rowan School of Osteopathic Medicine, Stratford, New Jersey, USA.
Maxwell JohnsonAnatomy and Neuroscience, Northeast Ohio Medical University, Rootstown, Ohio, USA.
Rebecca Z GermanAnatomy and Neuroscience, Northeast Ohio Medical University, Rootstown, Ohio, USA.ORCID 0000-0001-9989-7847
Northeast Ohio Medical University · USRowan University · USNorthern Arizona University · USTulane University · US

Funding

The effect of sensory intervention on swallowing and respiration through neurological maturation in preterm infantsR01HD096881 · NICHD · NORTHEAST OHIO MEDICAL UNIVERSITY · PI GERMAN, REBECCA Z · 2019 to 2023
$2.9M
The impact of biomimetic nipple on infant feeding functionR00HD105922 · NICHD · NORTHERN ARIZONA UNIVERSITY · PI MAYERL, CHRISTOPHER · 2022 to 2024
$720k
NICHD NIH HHS R00 HD105922NICHD NIH HHS R01 HD096881
6 · The paper itself

Abstract

The coordination of respiration and swallowing is a life-critical function in infants. Varying volume and rate of milk delivery changes swallowing frequency and bolus volume but any impact on swallow-respiration coordination is unknown. Five infant pigs were filmed with simultaneous high speed videofluoroscopy and plethysmography while feeding from an automatic system delivering milk across a range of volumes and frequencies. Swallow inspiration delay, respiratory cycle duration, and distribution of inspiratory and expiratory swallows were calculated. At constant volume, there were more inspiratory phase swallows when frequency increased. At high constant frequency, increasing volume changed swallow-respiration coordination patterns, with increased occurrence of inspiratory phase swallows. Respiratory cycle duration did not change in response to changes in oral milk delivery. These results suggest that the observed pattern of expiratory swallowing in infants is achieved primarily by regulation of milk intake, not modulation of respiratory patterns by oral sensation.

Indexed as

DeglutitionMilkAnimalsRespirationSwinecoordinationdysphagiainfantrespirationswallow

Identifiers

PMID37653670
PMCPMC11321598
OpenAlexW4386347208

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.