Observational studyJournal of orthopaedic surgery and research2023
D-dimer-albumin ratio (DAR) as a new biomarker for predicting preoperative deep vein thrombosis after geriatric hip fracture patients.
Observational study in Journal of orthopaedic surgery and research, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed, 10 citations in OpenAlex.
- Peri-Diagnostic D-Dimer-to-Albumin Ratio and Intensive Care Unit Admission in Pulmonary Embolism: A Single-Center Retrospective Cohort Study.Journal of clinical medicine · 2026Article
- Article
- The Association of the Neutrophil-to-Lymphocyte Ratio and the D-dimer-to-Albumin Ratio with Deep Vein Thrombosis in Patients with Spontaneous Intracerebral Hemorrhage.International journal of general medicine · 2026Article
- A Web-Based Machine Learning Calculator for Predicting Preoperative Deep Vein Thrombosis in Elderly Hip Fractures Patients.Clinical interventions in aging · 2026Article
- Dynamic Evolution Characteristics and Nursing Intervention Windows of Perioperative Deep Vein Thrombosis in Patients with Lower Extremity Traumatic Fractures: A Prospective Cohort Study.Therapeutics and clinical risk management · 2026Article
- Article
- Impact of the Geriatric Nutritional Risk Index on In-hospital Thrombosis and Mortality in Patients Hospitalized with COVID-19.Internal medicine (Tokyo, Japan) · 2025Article
- Association between D-dimer-to-albumin ratio and 28-days all-cause mortality in patients with sepsis.Scientific reports · 2024Article
- Article
- Clinical significance and underlying mechanism of long non-coding RNA SNHG12 in lower extremity deep venous thrombosis.Clinical and translational science · 2024Article
- Integrating deep learning in public health: a novel approach to PICC-RVT risk assessment.Frontiers in public health · 2024Article
- Predictive Value of D-Dimer for In-Hospital Mortality in Non-Diabetic Patients with Non-ST-segment Elevation Myocardial Infarction.Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/HemostasisArticle
- New Predictive Model and Predictors for Perioperative Deep Vein Thrombosis Formation in Fractures of the Lower Extremity Versus Traditional Scoring.Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/HemostasisArticle
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeHip fractures in the elderly are complicated by preoperative deep vein thrombosis (DVT). The objective of this study is to determine the usefulness of blood-based biomarkers, particularly the D-dimer-albumin ratio (DAR), in predicting preoperative DVT.
methodsA retrospective observational study was carried out on 1149 patients from a single hospital, and subsequently validated on an additional 626 patients from a separate hospital. The aim was to evaluate the prognostic and predictive value of 10 biomarkers, with a specific emphasis on DAR, in both cohorts. The primary measure of interest was the occurrence of preoperative DVT.
resultsThe ratio of D-dimer to albumin demonstrated superior predictive capability for preoperative DVT in older patients with hip fractures compared to other biomarkers (AUC = 0.677). Using the optimal cutoff point of 0.24, high DAR was significantly associated with preoperative DVT (OR 3.45, 95% CI 2.00-5.95). Notably, all the DAR definitions detailed above were successfully validated in an external, independent cohort.
conclusionsDAR may be a valuable biomarker for predicting preoperative DVT in elderly patients with hip fractures.
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