Evidence map›Paper›PMID 37653503›Full record

SynthesisBMC gastroenterology2023

Association between tea consumption and colorectal cancer: a systematic review and meta-analysis of a population-based study.

Yu Huang, Qiang Chen, Yating Liu, Ruoxi Tian, Xu Yin, Yaoguang Hao, Yang Yang, Jian Yang, Zongxuan Li, Suyang Yu and 2 more

Open access · goldAbstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in BMC gastroenterology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
2.0field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it, 8 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 1 country.

Yu Huang *Department of Gastrointestinal Surgery, The Third Hospital of Hebei Medical University, Shijiazhuang, 050051, P.R. China.
Qiang Chen *Department of Gastrointestinal Surgery, The Third Hospital of Hebei Medical University, Shijiazhuang, 050051, P.R. China.
Yating LiuDepartment of Gastrointestinal Surgery, The Third Hospital of Hebei Medical University, Shijiazhuang, 050051, P.R. China.
Ruoxi TianDepartment of Clinical Medical College, Tianjin Medical University, Tianjin, P.R. China.
Xu YinDepartment of Gastrointestinal Surgery, The Third Hospital of Hebei Medical University, Shijiazhuang, 050051, P.R. China.
Yaoguang HaoDepartment of Gastrointestinal Surgery, The Third Hospital of Hebei Medical University, Shijiazhuang, 050051, P.R. China.
Yang YangDepartment of Gastrointestinal Surgery, The Third Hospital of Hebei Medical University, Shijiazhuang, 050051, P.R. China.
Jian YangDepartment of Thoracic Surgery Gastrointestinal Surgery, the Third Hospital of Hebei Medical University, Shijiazhuang, P.R. China.
Zongxuan LiDepartment of Vascular Surgery Gastrointestinal Surgery, the Third Hospital of Hebei Medical University, Shijiazhuang, P.R. China.
Suyang YuDepartment of Gastrointestinal Surgery, The Third Hospital of Hebei Medical University, Shijiazhuang, 050051, P.R. China. ysyqtt@163.com.
Hongyan LiDepartment of Gastrointestinal Surgery, The Third Hospital of Hebei Medical University, Shijiazhuang, 050051, P.R. China. windhbyd@126.com.
Guiying WangDepartment of Gastrointestinal Surgery, The Third Hospital of Hebei Medical University, Shijiazhuang, 050051, P.R. China. wangguiying@hebmu.edu.cn.
Hebei Medical University · CNThird Hospital of Hebei Medical University · CNTianjin Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeA meta-analysis study was performed to systematically assess the association between tea consumption and CRC risk.

methodsCochrane Library, Embase, PubMed, and Web of Science were retrieved to collect articles in English since 24 July 2023. Databases were searched and evaluated by two reviewers independently.We screened the literature based on inclusion and exclusion criteria. After determining the random effect model or fixed utility model based on a heterogeneity test, odds ratios (ORs) and 95% confidence intervals (CIs) were calculated.

resultsWe included fourteen articles in this meta-analysis. We analyzed the data using a random effect model to explore the association between tea consumption and CRC because of apparent heterogeneity (P < 0.001, I2 = 99.5%). The combined results of all tests showed that there is no statistically significant association between tea consumption and CRC risk (OR = 0.756, 95%CI = 0.470-1.215, P = 0.247). Subsequently, subgroup analysis and sensitivity analysis were performed. Excluding any single study, the overall results ranged from 0.73 (95%CI = 0.44-1.20) to 0.86 (95%CI = 0.53-1.40). It was determined that there was no significant publication bias between tea consumption and CRC risk (P = 0.064) by Egger's tests.

conclusionsThe results indicated that tea consumption may not be significantly associated with the development of CRC. IMPLICATIONS OF KEY

findingsTea reduces colon cancer risk by 24%, but the estimate is uncertain. The actual effect on risk can range from a reduction of 51% to an increase of 18%, but regional and population differences may cause differences.

Indexed as

Colonic NeoplasmsResearchDatabases, FactualHumansTeaTeaCRCMeta-analysisPopulation-based studySystematic reviewTea consumption

Identifiers

PMID37653503
PMCPMC10472699
OpenAlexW4386324901

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.