Evidence map›Paper›PMID 37653457›Full record

ArticleEye and vision (London, England)2023

Rates of infectious keratitis and other ocular surface adverse events in corneal cross-linking for keratoconus and corneal ectasias performed in an office-based setting: a retrospective cohort study.

Farhad Hafezi, Emilio A Torres-Netto, Leonard Kollros, Nan-Ji Lu, Nikki Hafezi, Cosimo Mazzotta, M Enes Aydemir, Mark Hillen

Erratum issuedOpen access · diamondAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Eye and vision (London, England), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.9field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 4 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 4 countries.

Farhad HafeziLaboratory for Ocular Cell Biology, Center for Applied Biotechnology and Molecular Medicine, University of Zurich, Zurich, Switzerland. farhad@hafezi.ch.ORCID http://orcid.org/0000-0001-8935-4558
Emilio A Torres-NettoELZA Institute, Dietikon, Switzerland.
Leonard KollrosELZA Institute, Dietikon, Switzerland.
Nan-Ji LuELZA Institute, Dietikon, Switzerland.
Nikki HafeziELZA Institute, Dietikon, Switzerland.
Cosimo MazzottaDepartmental Ophthalmology Unit, Alta Val d'Elsa Hospital, AUSL Tuscany South-East, Siena, Italy.
M Enes AydemirLaboratory for Ocular Cell Biology, Center for Applied Biotechnology and Molecular Medicine, University of Zurich, Zurich, Switzerland.
Mark HillenELZA Institute, Dietikon, Switzerland.
ELZA Institute · CHUniversity of Geneva · CHUniversity of Siena · ITUniversity of Zurich · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThis study aimed to compare the complication rates of epithelium-off corneal cross-linking (epi-off CXL) performed in an office-based setting with those of epi-off CXL performed in an operating room.

methodsA retrospective cohort study, comprising 501 consecutive epi-off CXL procedures, performed in a non-sterile procedure room without laminar flow ventilation at the ELZA Institute in Zurich, Switzerland, between November 2015 and October 2021, was conducted.

resultsNo cases of postoperative infectious keratitis were observed, while sterile infiltrates occurred in 10 out of 501 (2.00%) patients, all of whom responded well to topical steroid therapy. Delayed epithelialization (> 7 days) occurred in 14 out of 501 (2.79%) patients. No other adverse events were noted.

conclusionsOffice-based epi-off CXL does not appear to be associated with an increased risk of complications when compared to operating room settings.

Indexed as

CorneaCorneal cross-linkingEpithelium-offInfectious keratitisKeratoconusOffice-basedSlit lampSterile infiltrates

Identifiers

PMID37653457
PMCPMC10472555
OpenAlexW4386318589

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.