Evidence map›Paper›PMID 37653357›Full record

ArticleInternational urology and nephrology2024

Choosing the larger kidney on CT volumetry: a study on the early post-donation kidney function of living donors.

Lin Kyaw, Karthik Thandapani, Lynnette Tan, Hong Min Peng, Benjamin Goh, Jirong Lu, Lata Raman, Bee Choo Tai, Vathsala Anantharaman, Ho Yee Tiong

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Article in International urology and nephrology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

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1citing papers in PubMed
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1 · What the graph read from it

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3 · Its place in the literature

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1 citing paper in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

10 authors.

Lin KyawDepartment of Urology, National University Hospital, 5 Lower Kent Ridge Rd, Singapore, 119074, Singapore.
Karthik ThandapaniDivison of Urology, Ng Teng Fong General Hospital, Singapore, Singapore.
Lynnette TanDepartment of Urology, National University Hospital, 5 Lower Kent Ridge Rd, Singapore, 119074, Singapore.
Hong Min PengYong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.
Benjamin GohDepartment of Urology, National University Hospital, 5 Lower Kent Ridge Rd, Singapore, 119074, Singapore.
Jirong LuDepartment of Urology, National University Hospital, 5 Lower Kent Ridge Rd, Singapore, 119074, Singapore.
Lata RamanDepartment of Urology, National University Hospital, 5 Lower Kent Ridge Rd, Singapore, 119074, Singapore.
Bee Choo TaiSchool of Public Health, National University Singapore, Singapore, Singapore.
Vathsala AnantharamanYong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.
Ho Yee TiongDepartment of Urology, National University Hospital, 5 Lower Kent Ridge Rd, Singapore, 119074, Singapore. surthy@nus.edu.sg.ORCID http://orcid.org/0000-0003-0077-7904

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundSelecting the smaller kidney for donation has been advocated if there is a size difference of > 10% between the 2 kidneys but has never been prospectively evaluated. With increase in donor nephrectomies, it is important to evaluate this to minimize loss of renal function to donors.

methods75 consecutive donor nephrectomy patients were included in our longitudinal study. The Split Renal Volume (SRV) of bilateral kidneys were measured using contrasted computer tomography scans and patients segregated into 2 groups depending on donated kidney having more (Group 1) or less than (Group 2) 52.5% of SRV.

resultsPatients in Group 1 (n = 19) and 2 (n = 56) were of similar age (43.8 vs. 48.3), BMI (22.4 vs. 25.2), sex (57.9 vs. 55.4% women), respectively. Although total kidney volumes were similar in both groups, Group 1 had significantly smaller right kidney volumes (120.4 ± 24.9 vs. 142.7 ± 28.4 mls, p = 0.003). EGFR pre-operatively (116.3 ± 20.8 vs. 106.3 ± 23.8 mL/min/1.73 m

conclusionWith a SRV difference of 5% between the 2 sides, removal of the larger kidney for living kidney donation resulted in greater early decline of renal function than kidney donors whose larger or equivalent kidney is preserved.

Indexed as

Kidney TransplantationFemaleGlomerular Filtration RateHumansKidneyLiving DonorsLongitudinal StudiesMaleNephrectomyRetrospective StudiesTomography, X-Ray ComputedDonor kidney sizeDonor kidney volumeKidney CT-volumetryKidney transplant

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.