ArticleNature plants2023
Ethylene produced in carpel primordia controls CmHB40 expression to inhibit stamen development.
Article in Nature plants, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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Who cites it
17 citing papers in PubMed, 31 citations in OpenAlex.
- Developmental and Molecular Insights into AgNOPlants (Basel, Switzerland) · 2026Article
- Unraveling the mystery of auxin-promoting femaleness in cucurbits.Horticulture research · 2026Article
- Temperature-dependent sex expression in cucurbits and beyond: mechanisms, reproductive plasticity, and breeding implications.Frontiers in plant science · 2026Review
- Ethylene promotes branch formation but inhibits tendril development in cucumber.Nature communications · 2025Article
- TaEPFL1 gene controls the development of wheat pistils and stamens by regulating ethylene synthesis.Plant molecular biology · 2025Article
- Several groups of LysM-RLKs are involved in symbiotic signal perception and arbuscular mycorrhiza establishment.Nature communications · 2025Article
- Advances in the Evolutionary Mechanisms and Genomic Studies of Sexual Differentiation in Lauraceae Plants.International journal of molecular sciences · 2025Review
- Developmental innovation of inferior ovaries and flower sex orchestrated by KNOX1 in cucurbits.Nature plants · 2025Article
- Ethylene in fruits: beyond ripening control.Horticulture research · 2024Article
- Article
- Harbinger transposon insertion in ethylene signaling gene leads to emergence of new sexual forms in cucurbits.Nature communications · 2024Article
- The transcription factor CpMYB62 controls the genetic network that leads to the determination of female flowers inHorticulture research · 2024Article
- Light Supplementation in Pitaya Orchards Induces Pitaya Flowering in Winter by Promoting Phytohormone Biosynthesis.International journal of molecular sciences · 2024Article
- Possibility of genome editing for melon breeding.Breeding science · 2024Article
- Article
- Comparative RNA-Seq Analysis between Monoecious and Androecious Plants Reveals Regulatory Mechanisms Controlling Female Flowering inInternational journal of molecular sciences · 2023Article
- Multi-Omics Analysis Reveals Intricate Gene Networks Involved in Female Development in Melon.International journal of molecular sciences · 2023Article
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Authors and funding
19 authors at 2 institutions in 1 country.
Funding
Abstract
Sex determination evolved to control the development of unisexual flowers. In agriculture, it conditions how plants are cultivated and bred. We investigated how female flowers develop in monoecious cucurbits. We discovered in melon, Cucumis melo, a mechanism in which ethylene produced in the carpel is perceived in the stamen primordia through spatially differentially expressed ethylene receptors. Subsequently, the CmEIN3/CmEIL1 ethylene signalling module, in stamen primordia, activates the expression of CmHB40, a transcription factor that downregulates genes required for stamen development and upregulates genes associated with organ senescence. Investigation of melon genetic biodiversity revealed a haplotype, originating in Africa, altered in EIN3/EIL1 binding to CmHB40 promoter and associated with bisexual flower development. In contrast to other bisexual mutants in cucurbits, CmHB40 mutations do not alter fruit shape. By disentangling fruit shape and sex-determination pathways, our work opens up new avenues in plant breeding.
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