Evidence map›Paper›PMID 37653216›Full record

ArticleAnalytical sciences : the international journal of the Japan Society for Analytical Chemistry2023

Rapid determination of domoic acid in seafood by fluorescence polarization immunoassay using a portable analyzer.

Yu Ogura, Mao Fukuyama, Motohiro Kasuya, Koji Shigemura, Sergei A Eremin, Manabu Tokeshi, Akihide Hibara

Open access · hybridAbstract read
In one paragraph

Article in Analytical sciences : the international journal of the Japan Society for Analytical Chemistry, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.6field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Determination of okadaic acid in scallop using microfluidic-based fluorescence polarization immunoassay.Analytical sciences : the international journal of the Japan Society for Analytical Chemistry · 2026
    Article
  2. Recent technical development for on-site analysis.Analytical sciences : the international journal of the Japan Society for Analytical Chemistry · 2024
    Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 5 institutions in 2 countries.

Yu OguraInstitute of Multidisciplinary Research for Advanced Materials, Tohoku University, Sendai, Japan.
Mao FukuyamaInstitute of Multidisciplinary Research for Advanced Materials, Tohoku University, Sendai, Japan. maofukuyama@tohoku.ac.jp.ORCID http://orcid.org/0000-0002-3330-0793
Motohiro KasuyaFaculty of Production Systems Engineering and Sciences, Komatsu University, Komatsu, Japan.
Koji ShigemuraTianma Japan, Ltd., Kawasaki, Japan.
Sergei A EreminBach Institute of Biochemistry, Research Centre of Biotechnology, Russian Acad. Sci, Moscow, Russia.
Manabu TokeshiDivision of Applied Chemistry, Faculty of Engineering, Hokkaido University, Sapporo, Japan.
Akihide HibaraInstitute of Multidisciplinary Research for Advanced Materials, Tohoku University, Sendai, Japan. hibara.a.aa@m.titech.ac.jp.
Tohoku University · JPA N Bach Institute of Biochemistry · RUHokkaido University · JPKomatsu University · JPTokyo Institute of Technology · JP

Funding

Ministry of Agriculture, Forestry and Fisheries JPJ008837Russian Science Foundation Project 20-43-07001
6 · The paper itself

Abstract

Monitoring phycotoxin accumulation in marine products such as edible shellfish is a regulatory requirement in many countries. Therefore, a simple and rapid onsite quantification method is sought. Herein, we present a fluorescence polarization immunoassay (FPIA), a well-known one-step immunoassay, using a portable fluorescence polarization analyzer for domoic acid (DA), widely referred to as the primary toxin of amnesic shellfish poisoning (ASP). To establish FPIA for DA, the matrix effect of methanol, which is widely used to extract DA from shellfish, on FPIA was investigated. To validate this method, we performed a spike recovery test using oysters containing DA at a concentration equivalent to the regulatory limits of North America and the European Union (20 mg/kg). The recovery rate was found to be 79.4-114.7%, which is equivalent to that of the commercially available enzyme-linked immunosorbent assay (ELISA). We expect that this FPIA system will enable the quantitative onsite analysis of DA and significantly contribute to the safety of marine products.

Indexed as

Marine ToxinsShellfishFluorescence Polarization ImmunoassayKainic AcidSeafooddomoic acidKainic AcidMarine ToxinsImmunoassayOnsite analysisPhycotoxinShellfish poisoning

Identifiers

PMID37653216
PMCPMC10667144
OpenAlexW4386318252

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.