Evidence map›Paper›PMID 37653211›Full record

ArticleJournal of general internal medicine2023

Inpatient Hepatitis C Treatment Coordination and Initiation for Patients Who Inject Drugs.

L Madeline McCrary, Kate E Roberts, Mary Catherine Bowman, Briana Castillo, Jama M Darling, Christine Dunn, Robyn Jordan, Jane E Young, Asher J Schranz

Open access · bronzeAbstract read
In one paragraph

Article in Journal of general internal medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
2.9field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 14 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

L Madeline McCraryDepartment of Medicine, University of North Carolina, Chapel Hill, NC, USA. mccrary@wustl.edu.
Kate E RobertsGraduate School of Social Work and Social Research, Bryn Mawr College, Bryn Mawr, PA, USA.
Mary Catherine BowmanDepartment of Medicine, University of North Carolina, Chapel Hill, NC, USA.
Briana CastilloDepartment of Medicine, University of North Carolina, Chapel Hill, NC, USA.
Jama M DarlingDepartment of Medicine, University of North Carolina, Chapel Hill, NC, USA.
Christine DunnDepartment of Psychiatry, University of North Carolina, Chapel Hill, NC, USA.
Robyn JordanDepartment of Psychiatry, University of North Carolina, Chapel Hill, NC, USA.
Jane E YoungDepartment of Psychiatry, University of North Carolina, Chapel Hill, NC, USA.
Asher J SchranzDepartment of Medicine, University of North Carolina, Chapel Hill, NC, USA.
University of North Carolina at Chapel Hill · USBryn Mawr College · US

Funding

Drug-use associated infective endocarditis: Post-hospitalization outcomes and patient treatment preferencesK23DA049946 · NIDA · UNIV OF NORTH CAROLINA CHAPEL HILL · PI SCHRANZ, ASHER JACOB · 2020 to 2024
$880k
NIDA NIH HHS K23 DA049946NIDA NIH HHS K23DA049946
6 · The paper itself

Abstract

backgroundWith hepatitis C (HCV) incidence rising due to injection drug use, people who inject drugs (PWID) are a priority population for direct-acting antivirals (DAA). However, significant barriers exist. At our institution, hospitalized PWID were screened for HCV but not effectively linked to care.

aimTo improve retention in HCV care among hospitalized PWID.

settingQuaternary academic center in the Southeast US from August 2021 through August 2022.

participantsHospitalized PWID with HCV. PROGRAM DESCRIPTION: E-consultation-prompted care coordination and HCV treatment with outpatient telehealth. PROGRAM EVALUATION: Care cascades were constructed to assess retention and HCV treatment, with the primary outcome defined as DAA completion or sustained virologic response after week 4. Of 28 patients, 11 started DAAs inpatient, 8 initiated outpatient, and 9 were lost to follow-up or transferred care. Overall, 82% were linked to care and 52% completed treatment. For inpatient initiators, 73% achieved the outcome. Of non-inpatient initiators, 71% were linked to care, 53% started treatment, and 36% achieved the outcome. DISCUSSION: Inpatient HCV treatment coordination, including DAA initiation, and telehealth follow-up, was feasible and highly effective for hospitalized PWID. Future steps should address barriers to inpatient DAA treatment and expand this model to other similar patient populations.

Indexed as

Hepatitis CHepatitis C, ChronicSubstance Abuse, IntravenousAntiviral AgentsHepacivirusHumansInpatientsAntiviral Agentshepatitis Chospitalizationinjection drug usesubstance use

Identifiers

PMID37653211
PMCPMC10682347
OpenAlexW4386346979

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.