Evidence map›Paper›PMID 37653026›Full record

ArticleSchizophrenia (Heidelberg, Germany)2023

Are informants required to obtain valid ratings on the Positive and Negative Syndrome Scale (PANSS)?

Cecilie Marie Nielsen, Pernille Kølbæk, David Dines, Mark Opler, Christoph U Correll, Søren Dinesen Østergaard

Abstract read
In one paragraph

Article in Schizophrenia (Heidelberg, Germany), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Trial
  2. Trial
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Cecilie Marie NielsenPsychosis Research Unit, Aarhus University Hospital - Psychiatry, Aarhus, Denmark.ORCID http://orcid.org/0000-0002-7319-5115
Pernille KølbækPsychosis Research Unit, Aarhus University Hospital - Psychiatry, Aarhus, Denmark. perpet@rm.dk.
David DinesPsychosis Research Unit, Aarhus University Hospital - Psychiatry, Aarhus, Denmark.ORCID http://orcid.org/0000-0003-4140-6763
Mark OplerMedAvante-ProPhase Inc, New York, NY, USA.
Christoph U CorrellDivision of Psychiatry Research, The Zucker Hillside Hospital, Glen Oaks, NY, USA.
Søren Dinesen ØstergaardDepartment of Clinical Medicine, Aarhus University, Aarhus, Denmark.ORCID http://orcid.org/0000-0002-8032-6208

Funding

Det Frie Forskningsråd (Danish Council for Independent Research) 7016-00048BDet Frie Forskningsråd (Danish Council for Independent Research) 701600048B
6 · The paper itself

Abstract

Ratings on the Positive and Negative Syndrome Scale (PANSS) are ideally based on both a patient interview and an informant questionnaire. In research and clinical settings, however, the informant questionnaire is often omitted. This study investigated the consequences of omitting informant information by comparing PANSS ratings of patients with schizophrenia (n = 49 patients, 77 ratings) conducted with and without informant information, respectively. Additionally, changes in symptom severity over time based on ratings with and without informant information were also compared for the full PANSS and the six-item version of the PANSS (PANSS-6). PANSS ratings including informant information were higher than those without, both at the total score and individual item level. Additionally, the full PANSS appeared less "responsive" to baseline-to-endpoint changes for ratings without informant information compared to ratings including informant information, while no differences were found for the PANSS-6.

Identifiers

PMID37653026
PMCPMC10471695

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.