Evidence map›Paper›PMID 37652864›Full record

ArticleAcute and critical care2023

Radiomic analysis of abdominal organs during sepsis of digestive origin in a French intensive care unit.

Louis Boutin, Louis Morisson, Florence Riché, Romain Barthélémy, Alexandre Mebazaa, Philippe Soyer, Benoit Gallix, Anthony Dohan, Benjamin G Chousterman

Open access · diamondAbstract read
In one paragraph

Article in Acute and critical care, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact, top 72% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 0 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 2 countries.

Louis BoutinDepartment of Anesthesiology and Critical Care, Hôpital Lariboisière, AP-HP, Paris, France.
Louis MorissonDepartment of Anesthesiology and Critical Care, Hôpital Lariboisière, AP-HP, Paris, France.
Florence RichéDepartment of Anesthesiology and Critical Care, Hôpital Lariboisière, AP-HP, Paris, France.
Romain BarthélémyDepartment of Anesthesiology and Critical Care, Hôpital Lariboisière, AP-HP, Paris, France.
Alexandre MebazaaDepartment of Anesthesiology and Critical Care, Hôpital Lariboisière, AP-HP, Paris, France.
Philippe SoyerINSERM UMR-S 942, MASCOT, Université Paris Cité, Paris, France.
Benoit GallixIHU Strasbourg, Strasbourg, France.
Anthony DohanINSERM UMR-S 942, MASCOT, Université Paris Cité, Paris, France.
Benjamin G ChoustermanDepartment of Anesthesiology and Critical Care, Hôpital Lariboisière, AP-HP, Paris, France.
Inserm · FRAssistance Publique – Hôpitaux de Paris · FRInstitut de Chirurgie Guidée par l'Image · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundSepsis is a severe and common cause of admission to the intensive care unit (ICU). Radiomic analysis (RA) may predict organ failure and patient outcomes. The objective of this study was to assess a model of RA and to evaluate its performance in predicting in-ICU mortality and acute kidney injury (AKI) during abdominal sepsis.

methodsThis single-center, retrospective study included patients admitted to the ICU for abdominal sepsis. To predict in-ICU mortality or AKI, elastic net regularized logistic regression and the random forest algorithm were used in a five-fold cross-validation set repeated 10 times.

resultsFifty-five patients were included. In-ICU mortality was 25.5%, and 76.4% of patients developed AKI. To predict in-ICU mortality, elastic net and random forest models, respectively, achieved areas under the curve (AUCs) of 0.48 (95% confidence interval [CI], 0.43-0.54) and 0.51 (95% CI, 0.46-0.57) and were not improved combined with Simplified Acute Physiology Score (SAPS) II. To predict AKI with RA, the AUC was 0.71 (95% CI, 0.66-0.77) for elastic net and 0.69 (95% CI, 0.64-0.74) for random forest, and these were improved combined with SAPS II, respectively; AUC of 0.94 (95% CI, 0.91-0.96) and 0.75 (95% CI, 0.70-0.80) for elastic net and random forest, respectively.

conclusionsThis study suggests that RA has poor predictive performance for in-ICU mortality but good predictive performance for AKI in patients with abdominal sepsis. A secondary validation cohort is needed to confirm these results and the assessed model.

Indexed as

acute kidney injurycomputed tomographyimage processingintensive care unitsepsis

Identifiers

PMID37652864
PMCPMC10497895
OpenAlexW4386028437

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LicenceCC BY-NC
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.